Sex differences in acetylcholine-induced sweating responses due to physical training.

Purpose: The present study examined sex differences in the sweat gland response to acetylcholine (ACh) in physically trained and untrained male and female subjects.

Methods: Sweating responses were induced on the forearm and thigh in resting subjects by ACh iontophoresis using a 10% solution at 2 mA for 5 min at 26°C and 50% relative humidity.

Results: The ACh-induced sweating rate (SR) on the forearm and thigh was greater in physically trained male (P < 0.