Genomic Characterization Provides New Insights Into the Biosynthesis of the Secondary Metabolite Huperzine a in the Endophyte Cg01.

A reliable source of Huperzine A (HupA) meets an urgent need due to its wide use in Alzheimer's disease treatment. In this study, we sequenced and characterized the whole genomes of two HupA-producing endophytes, hy4 and Cg01, to clarify the mechanism of HupA biosynthesis. The whole genomes of hy4 and Cg01 were 33.

Genome and secretome analysis of Pochonia chlamydosporia provide new insight into egg-parasitic mechanisms.

Pochonia chlamydosporia infects eggs and females of economically important plant-parasitic nematodes. The fungal isolates parasitizing different nematodes are genetically distinct. To understand their intraspecific genetic differentiation, parasitic mechanisms, and adaptive evolution, we assembled seven putative chromosomes of P.

Complete mitogenome of the high ethanol production fungus Mh2-2.

spp. are significantly important plant pathogens, and some of them are ethanol-producing strains. During infection and/or ethanol production, requires a plenty of energy that is mainly provided by mitochondria.

The complete mitochondrial genome of huperzine A-producing endophytic fungus .

Huperzine A-producing fungus Hy4 (CCTCC No.M2010086) was isolated from (Thunb) Trev. The complete mitochondrial genome of is 28 192 bp in length, containing 15 protein-encoding genes, 27 tRNA genes and two rRNA genes.

Analysis of the complete mitochondrial genome of Pochonia chlamydosporia suggests a close relationship to the invertebrate-pathogenic fungi in Hypocreales.

Background: The fungus Pochonia chlamydosporia parasitizes nematode eggs and has become one of the most promising biological control agents (BCAs) for plant-parasitic nematodes, which are major agricultural pests that cause tremendous economic losses worldwide. The complete mitochondrial (mt) genome is expected to open new avenues for understanding the phylogenetic relationships and evolution of the invertebrate-pathogenic fungi in Hypocreales.

Results: The complete mitogenome sequence of P.