Publications by authors named "Chibuzor F Ogamba"
Background: Cervical cancer is the second most common cancer among women in Nigeria where, the gap between need for, and access to, radiation therapy including brachytherapy is significant. This report documents the implementation of the first three-dimensional high-dose-rate (3D-HDR) brachytherapy service for cervical cancer in Nigeria.
Purpose: This report details the steps taken to implement the 3D-HDR brachytherapy program, the challenges faced, and the adaptive strategies employed to overcome them.
Article Synopsis
- The UK Biobank data allows researchers to study links between plasma proteins and cancer risks, analyzing 1463 proteins across 19 cancers over an average follow-up of 12 years.
- Out of 618 identified protein-cancer associations, 107 were persistent for diagnoses occurring more than seven years after initial blood draw, indicating potential early indicators of cancer risk.
- Four specific proteins (CD74, TNFRSF1B, ADAM8, SFTPA2) showed strong connections to different cancers, suggesting they could play a role in cancer development and risk prediction.
Background: Advances in precision medicine in Nigeria suggest improving genomics education and competency among healthcare practitioners to facilitate clinical translation. Due to the scarcity of research in this area, this study aimed to assess Nigerian medical students' perceptions about their preparedness to integrate precision medicine into their future clinical practice.
Methods: This was an institution-based cross-sectional study of medicine and surgery students in their clinical years attending the two fully accredited colleges of medicine in Lagos, Nigeria, between April and October 2022 using an adapted tool administered via Google Forms.
Background: Anemia is a public health problem affecting people in both the developed and developing world and has serious consequences on health.
Objective: This study determines the prevalence of anemia amongst people of different socioeconomic levels, associated factors, and the prevalence of anemia in populations other than children or pregnant women.
Methods: This is a descriptive cross-sectional study using a pretested interviewer-administered questionnaire to collect data from 387 residents.
Haematological indices and coagulation profile as predictors of disease severity and associations with clinical outcome among COVID-19 patients in Lagos, Nigeria.
Ann Afr Med
April 2023
Background: This study aims to evaluate the use of haematological indices and coagulation profiles as possible low-cost predictors of disease severity and their associations with clinical outcomes in COVID-19-hospitalized patients in Nigeria.
Materials And Methods: We carried out a hospital-based descriptive 3-month observational longitudinal study of 58 COVID-19-positive adult patients admitted at the Lagos University Teaching Hospital, Lagos, Nigeria. We used a structured questionnaire to obtain the participants' relevant sociodemographic and clinical data, including disease severity.
Background: Strategies involved in the prevention and management of sickle cell disease include premarital genotype screening and counselling as well as efforts at increasing the knowledge of the population about the condition.
Methodology: This is a cross-sectional descriptive study which assessed the knowledge of sickle cell disease and premarital genotype screening, attitudes towards screening and factors associated with uptake of premarital genotype screening among 326 final year students at the University of Ibadan, Oyo State, Nigeria.
Results: Respondents were within the age range of 18-24 with a mean age of 23.
Background Sickle cell disease (SCD) is a genetic disease of public health concern. Improved quality healthcare has increased the life expectancy of these patients; however, they also face an increased frequency of vaso-occlusive crises and other SCD complications. These complications affect their quality of life, an area of care, which healthcare providers often overlook.
View Article and Find Full Text PDFKnowledge, attitudes, and decision making towards prenatal testing among antenatal clinic attendees in Lagos University Teaching Hospital: an institution-based cross-sectional study.
Pan Afr Med J
October 2021
Article Synopsis
- * Conducted with 422 participants, the research finds that most women had fair knowledge and good attitudes towards prenatal screening, but only 18.2% were willing to terminate affected pregnancies.
- * Significant correlations were observed between socio-demographic factors, such as marital status and knowledge levels, suggesting the need for further research on the ethical beliefs influencing these decisions.
Article Synopsis
- - The study investigates the knowledge of pregnant women regarding birth defects and their willingness to participate in prenatal screening tests at Lagos University Teaching Hospital, highlighting the role of education in this context.
- - Among 422 participants, most had at least secondary education, with an average knowledge score of 63%; employed women showed higher knowledge, while those with lower education had diminished awareness and willingness to screen.
- - The findings underline significant gaps in knowledge, suggesting that enhancing education and access to healthcare can empower women to better understand and engage with prenatal screening options.
Introduction: there is a paucity of data on the financial implications of sickle cell disease on households of affected children and their use of health insurance in Nigeria. This study assessed the awareness of health insurance, patterns of health service utilization and financial implications of sickle cell disease among children seeking care at a tertiary facility in Nigeria.
Methods: a structured questionnaire was administered to parents of 314 children with sickle cell disease attending the pediatric hematology unit of the Lagos University Teaching Hospital between May and December 2019.