Publications by authors named "Chiara Wernecke"
Article Synopsis
- Spaceflight presents unique health risks for astronauts, particularly regarding skin health, which are not yet fully understood.
- A comprehensive analysis using various biological datasets revealed significant changes in skin-related biological processes during spaceflight, including DNA damage and mitochondrial issues.
- The study's results emphasize the potential for developing strategies to reduce skin damage from space travel and highlight the body's ability to adapt back to Earth's conditions after missions.
Spaceflight poses a unique set of challenges to humans and the hostile Spaceflight environment can induce a wide range of increased health risks, including dermatological issues. The biology driving the frequency of skin issues in astronauts is currently not well understood. To address this issue, we used a systems biology approach utilizing NASA's Open Science Data Repository (OSDR) on spaceflown murine transcriptomic datasets focused on the skin, biomedical profiles from fifty NASA astronauts, and confirmation via transcriptomic data from JAXA astronauts, the NASA Twins Study, and the first civilian commercial mission, Inspiration4.
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