Publications by authors named "Chiara Scorziello"

Given the long-standing debate about the nature of the concept of disease, the objective of this study was to understand how doctors categorize a condition as a disease or not, and what the kind of information they use is. A survey with a set of eighteen clinical vignettes was designed, and nineteen physicians and senior students purposefully selected were asked to interpret those situations as diseases or not and to produce an anonymous short written piece of text providing the motivation of their choice. Realist thematic analysis was used to analyse the answers, and four themes emerged: the temporal dimension of a disease, reification of disease, disease as an existential condition, and disease as a motivation to action.

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Incidental sonographic discovery of thyroid nodules is an increasingly common event in clinical practice. Less frequently, patients with cytological benign thyroid nodules have suspicious cervical lymph nodes detected by ultrasound examination or by cytological exam. Here, we discuss an intriguing case of cervical lymph node metastasis with a probable thyroid origin in a 65-year-old asymptomatic male smoker.

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Article Synopsis
  • The study evaluated whether the size of thyroid nodules can predict malignancy as effectively as other factors like composition, echogenicity, and shape, in line with ACR guidelines for fine-needle aspiration biopsy (FNAB).
  • Conducted on 86 patients, the research involved categorizing nodules based on size and calculating diagnostic metrics like sensitivity, specificity, and predictive values across different sub-classes.
  • Findings indicated no significant difference in the prediction of malignancy based on size categories, suggesting that the importance of size may not be as clear-cut as the ACR guidelines imply in standardized thyroid assessments.
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Background and Objectives: Recurrent laryngeal nerve (RLN) paralysis is a fearful complication during thyroidectomy. Intraoperative neuromonitoring (IONM) and optical magnification (OM) facilitate RLN identification and dissection. The purpose of our study was to evaluate the influence of the two techniques on the incidence of RLN paralysis and determine correlations regarding common outcomes in thyroid surgery.

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Introduction: Improving the prognosis of breast cancer patients is of utmost importance in terms of increasing survival rates. Modern medicine has therefore prioritized better quality of life for patients, even after the disease, through a better management of the potential long-term side effects induced by anticancer treatments. Fertility preservation and family planning are therefore crucial issues to be addressed in all cancer patients of reproductive age.

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Article Synopsis
  • Family history of thyroid cancer is linked to a higher risk of extrathyroidal extension (ETE) and multifocality in thyroid malignancies, prompting some experts to recommend more aggressive surgical techniques.* -
  • This study aimed to determine if neck ultrasonography could effectively identify or rule out multifocality and ETE in patients with a first-degree relative who had thyroid cancer.* -
  • Results showed that while ultrasonography has some predictive value for multifocality and ETE, it is not reliable enough to exclude these features before surgery, suggesting that negative ultrasound findings do not guarantee the absence of these complications.*
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There is controversy in the literature regarding a distinct subset of thyroid carcinoma whose histologically classification falls between well-differentiated and anaplastic carcinomas, previously identified as 'poorly differentiated thyroid carcinoma' (PDTC), or 'insular carcinoma', in view of the peculiar morphological characteristics of the cell groupings. The correct diagnosis and treatment of this entity have important prognostic and therapeutic significance. In this review, we describe the epidemiology, diagnosis, and management of PDTC and report our single centre experience to add to the limited evidence existing in the literature.

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