Is the Imitative Competence an Asymmetrically Distributed Function?

This study reconsiders behavioral and functional data from studies investigating the anatomical imitation (AI) and the related mental rotation (MR) competence, carried out by our group in healthy subjects, with intact interhemispheric connections, and in split-brain patients, completely or partially lacking callosal connections. The results strongly point to the conclusion that AI and MR competence requires interhemispheric communication, mainly occurring through the corpus callosum, which is the largest white matter structure in the human brain. The results are discussed in light of previous studies and of future implications.

Functional MRI cortical activations from unilateral tactile-taste stimulations of the tongue.

Functional magnetic resonance imaging (fMRI) was used for revealing activations in the human brain by lateralized tactile-gustatory stimulations of the tongue. Salt, a basic taste stimulus, and water, now recognized as an independent taste modality, were applied to either hemitongues with pads similar to the taste strips test for the clinical psychophysical evaluation of taste. With both stimuli, the observed cortical patterns of activations could be attributed to a combined somatosensory and gustatory stimulation of the tongue, with no significant differences between salt and water.

Functional topography of the corpus callosum investigated by DTI and fMRI.

This short review examines the most recent functional studies of the topographic organization of the human corpus callosum, the main interhemispheric commissure. After a brief description of its anatomy, development, microstructure, and function, it examines and discusses the latest findings obtained using diffusion tensor imaging (DTI) and tractography (DTT) and functional magnetic resonance imaging (fMRI), three recently developed imaging techniques that have significantly expanded and refined our knowledge of the commissure. While DTI and DTT have been providing insights into its microstructure, integrity and level of myelination, fMRI has been the key technique in documenting the activation of white matter fibers, particularly in the corpus callosum.

Mirror-image discrimination and reversal in the disconnected hemispheres.

Two callosotomized patients and 24 neurologically normal subjects performed simple binary discriminations between upright letters flashed in one or other visual field. Where discrimination of the letters F and R by name either showed a left-hemisphere advantage or no hemispheric effect, discrimination of whether the same letters were normal or backward showed a right-hemisphere advantage. These results suggest that discrimination of mirror-image letters depends on matching to an exemplar, for which the right-hemisphere is dominant, while letter naming depends on abstract category recognition.