Synopsis of recent research by authors named "Chiara Paiardi"
- Chiara Paiardi's research primarily focuses on cellular processes and mechanisms related to neurodegenerative diseases, particularly Huntington's disease, and reproductive biology, with an emphasis on autophagy and lysosomal function in neurons.
- Her work demonstrates that Glutamine Synthetase 1 can enhance autophagy to alleviate symptoms associated with mutant Huntingtin aggregates, thereby improving motility in Huntington's disease models.
- Additionally, her studies on acrosome biogenesis in sperm reveal critical insights into infertility mechanisms, highlighting the roles of various proteins in cellular trafficking and organelle formation during spermatogenesis.
