Microbiological Analysis of Plaque and Its Composition in Three Patient Groups under Different Orthodontic Treatments.

Background: This article analyzes differences in microbiological parameters and periodontal health conditions among three patient groups: those undergoing conventional orthodontic treatment with fixed appliances, patients undergoing orthodontic treatment with clear aligners, and a control group receiving no treatment.

Materials And Methods: In this study, 60 patients were enrolled. The microbiological analysis employed a qualitative and semi-quantitative methodology of bacterial morphotype analysis.

L. subsp. Essential Oils and Their Principal Constituents as Anticancer Agents.

L. subsp. , belonging to the Apiaceae family, is a species that grows in Europe, mainly in the Mediterranean regions.

Antitumor Effect of (Boraginaceae) Essential Oil through Inhibition of the Activity of the Topo II Enzyme in Acute Myeloid Leukemia.

It was previously shown that the antitumor and cytotoxic activity of the essential oil (EO) extracted from the aerial parts of appears to involve a pro-oxidant mechanism in hepatocellular carcinoma (HCC) and in triple-negative breast cancer (TNBC) cell lines. Its most abundant compound is a hydroxy-methyl-naphthoquinone isomer. Important pharmacological activities, such as antitumor, antibacterial, antifungal, antiviral and antiparasitic activities, are attributed to naphthoquinones, probably due to their pro-oxidant or electrophilic potential; for some naphthoquinones, a mechanism of action of topoisomerase inhibition has been reported, in which they appear to act both as catalytic inhibitors and as topoisomerase II poisons.

Evaluation of the effectiveness of a novel mouth rinse containing hyaluronic acid and hydrogen peroxide on gingivitis: A randomized pilot controlled trial.

Objective: To evaluate and compare the effectiveness of a mouth rinse with hydrogen peroxide (H O ) and hyaluronic acid (HA) versus a placebo mouth rinse on gingivitis.

Material And Methods: This was a 21-day, double blind, randomized, two-arm parallel allocation placebo-controlled trial of 50 study participants with a diagnosis of plaque-induced gingivitis. Patients were randomly allocated to the test group or the placebo group and were assessed at three time points over the course of the study by the same operator, at baseline (T0), 7 days (T1), and 21 days follow-up (T2).