Publications by authors named "Chiara Guastadisegno"
In order to investigate the possible role of Epstein-Barr virus (EBV) in systemic lupus erythematosus (SLE) and its associated oral lesions, a pilot case-control study was performed. A total of 31 patients (18 females and 13 males) were enrolled in the study and divided into two groups: group A included 16 patients with diagnosis of SLE and group B included 15 healthy individuals. Salivary swab samples were collected and subjected to molecular screening by real-time quantitative PCR (qPCR) for the detection of EBV DNA.
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- Epidemiologic studies indicate that parental occupations, pesticide use, environmental factors, and genetic variations may contribute to childhood acute leukemia (CAL).
- A study analyzed 116 CAL cases and 162 controls, finding increased risk associated with maternal pesticide use during pregnancy, proximity to treated fields, and fathers working as traffic wardens or police officers.
- The research also highlighted a significant association between CAL and the genetic polymorphism CYP2D6*4 in individuals with homozygous alleles, suggesting these factors could influence the development of CAL.
Background: Occupational exposure is known to play a role in the aetiology of lymphomas. The aim of the present work was to explore the occupational risk of the major B-cell lymphoma subtypes using a case-control study design.
Methods: From 2009 to 2014, we recruited 158 lymphoma cases and 76 controls in the provinces of Bari and Taranto (Apulia, Southern Italy).
Assessment of environmental and occupational exposure to heavy metals in Taranto and other provinces of Southern Italy by means of scalp hair analysis.
Environ Monit Assess
June 2016
The monitoring of heavy metals in industrialized areas to study their association with different occupational and environmental factors is carried out in different ways. In this study, scalp hair analysis was used for the assessment of exposure to these metals in the industrial city of Taranto, characterized by a severe environmental pollution. The highest median values were observed for aluminum, barium, cadmium, lead, mercury, and uranium.
View Article and Find Full Text PDFTumors occurring in the retrorectal space are heterogeneous and uncommon. Multiple embryologie remnants derived from a variety of tissues are found in this space and this explains the heterogeneous pathology of cysts and tumors that arise in retrorectal space. Presacral cysts are rare in adults.
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