Publications by authors named "Chiara Falcicchio"

: Psychological distress impacts 35-40% of cancer patients, significantly affecting their quality of life, treatment adherence, and relationships with healthcare professionals. Given this, there is a critical need to enhance nursing competencies to effectively monitor and address psychological distress. Previous studies have highlighted discrepancies in capabilities based on nurses' training status, emphasizing trained nurses' critical role in providing appropriate psycho-social referrals.

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Background: A virtual reality experience (VRE) could represent a viable non-pharmacological intervention to reduce and better manage the main factors of psychophysical distress related to the diagnosis and treatment of cancer.

Aim: The study was a two-arm randomized controlled trial conducted at the Regina Elena National Cancer Institute - IRCCS (Rome, Italy) from April 2019 to January 2020 to evaluate VRE impact in patients affected by breast or ovarian cancer. Before starting the first cycle of chemotherapy (CT), patients were randomized to receive the VRE (VRE arm) as "distraction therapy" or to entertain themselves with conventional means (control arm).

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Purpose: The major improvements in the diagnosis and treatment of colorectal cancer (CRC) over the past decades increased the patients' survival rates. Despite this, patients and clinicians still need to address the long-term physical and psychosocial effects over time. This paper aims to prospectively assess CRC patients' HR-QoL psychological distress and sexual functioning and identify clinical, demographic, and psychological predictors.

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Article Synopsis
  • The study highlights the physical and psychological challenges faced by breast cancer patients that necessitate individualized rehabilitation programs post-treatment.
  • The analysis of 5,538 women in Italy revealed that a significant majority (81.7%) received outpatient care, primarily focused on pathology-related interventions, while only a small fraction engaged in inpatient or intensive outpatient programs.
  • The findings indicate a gap in adequate rehabilitation services, particularly concerning psychosocial and cognitive support, suggesting a need for improved access and resources for breast cancer patients.
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The aim of this study was to investigate symptoms, their variation over time and their relationship with quality of life (QoL)/psychological distress in sarcoma patients, as few data regarding QoL and psychological distress in this set of patients are currently available. A total of 188 sarcoma patients from an Italian referral center were involved. Symptoms and financial difficulties were evaluated with the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire from the first treatment and over the follow-up period, up to 6 years.

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While the emotional response of healthcare providers during the COVID-19 pandemic has been extensively investigated in countries in the Far-East, little is known about the psychological impact and the associated emotional distress of healthcare providers in Italy, especially with regard to different regions. The aim of the "VIRARE" survey, which was addressed to all the healthcare providers in the Lazio region (central Italy) and, in particular, to those working in the oncology field, is to analyze their opinion on the impact and management of the pandemic, to better understand the level of their psychological distress. A global good psychological response of healthcare providers to the pandemic has emerged, independently from their different occupations in the oncology field.

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To investigate sarcoma patients' perception of quality of life and psychosocial distress across the different disease's stages.  Total 329 sarcoma patients were monitored from diagnosis up to a maximum of six consecutive follow-up visits. Functional status worsened over time with the lowest value after surgery and a full recovery not earlier than the second follow-up visit.

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In recent years, we have witnessed a growing interest in the prevention of the loss of reproductive efficacy in young women as a result of cancer or its treatments. Indeed, recent studies have shown that loss of fertility impacts deeply on young women and sometimes may be even more stressful than the cancer diagnosis itself. In fact, the risk of treatment-associated infertility and premature menopause is a major concern for patients.

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Little is known about the cancer related fatigue (CRF) along cancer course and risk factors that could predict CRF development and persistence in breast cancer (BC) survivors. This prospective study detected incidence, timing of onset, duration of CRF, impact on QoL and psychological distress. Seventy-eight early BC patients, undergoing chemotherapy (CT) followed or not by hormonal therapy were assessed for QoL and psychological distress by EORTC QLQC30 and HADs questionnaires.

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Article Synopsis
  • This study examined the rehabilitation care patterns and health service use among brain tumor patients diagnosed from 2008-2009 in the Lazio Region, focusing on patients' experiences in the first year post-diagnosis.
  • Out of 719 patients analyzed, only a small percentage received different types of rehabilitation: 12.8% underwent inpatient rehabilitation, while 3.1% had an outpatient intensive plan, and 11.8% accessed outpatient interventions.
  • The findings highlight that many brain tumor patients have unmet rehabilitation needs, suggesting that the absence of structured rehabilitation strategies may detrimentally affect their functional independence and overall quality of life.
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