Publications by authors named "Chiara Coletti"

Purpose: To optimize Relaxation along a Fictitious Field (RAFF) pulses for rotating frame relaxometry with improved robustness in the presence of and field inhomogeneities.

Methods: The resilience of RAFF pulses against and inhomogeneities was studied using Bloch simulations. A parameterized extension of the RAFF formulation was introduced and used to derive a generalized inhomogeneity-resilient RAFF (girRAFF) pulse.

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Purpose: To develop and evaluate a robust cardiac mapping sequence at 3 T, using Bloch-Siegert shift (BSS)-based preparations.

Methods: A longitudinal magnetization preparation module was designed to encode . After magnetization tip-down, off-resonant Fermi pulses, placed symmetrically around two refocusing pulses, induced BSS, followed by tipping back of the magnetization.

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Article Synopsis
  • - The study aims to enhance an adiabatic method for accurately measuring spin-lock relaxation in the heart using advanced MRI techniques at 3 Tesla (3T).
  • - Researchers optimized various adiabatic spin-lock (aSL) modules for better performance against magnetic field inhomogeneities and validated them through simulations and tests on phantoms and healthy subjects.
  • - Results indicated that the optimized aSL methods provided significantly improved image quality, precision, and reproducibility in relaxation time measurements compared to traditional methods, with specific modules showing the best performance in both healthy individuals and patients with cardiovascular conditions.
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This work highlights the importance of the Geogenic Radon Potential (GRP) component originated by degassing processes in fault zones. This Tectonically Enhanced Radon (TER) can increase radon concentration in soil gas and the inflow of radon in the buildings (Indoor Radon Concentrations, IRC). Although tectonically related radon enhancement is known in areas characterised by active faults, few studies have investigated radon migration processes in non-active fault zones.

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Multimodal platforms combining electrical neural recording and stimulation, optogenetics, optical imaging, and magnetic resonance (MRI) imaging are emerging as a promising platform to enhance the depth of characterization in neuroscientific research. Electrically conductive, optically transparent, and MRI-compatible electrodes can optimally combine all modalities. Graphene as a suitable electrode candidate material can be grown via chemical vapor deposition (CVD) processes and sandwiched between transparent biocompatible polymers.

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Magnetic Resonance Imaging (MRI) is the clinical gold standard for the assessment of myocardial viability but requires injection of exogenous gadolinium-based contrast agents. Recently, T-mapping has been proposed as a fully non-invasive alternative for imaging myocardial fibrosis without the need for contrast agent injection. However, its applicability at high fields is hindered by susceptibility to MRI system imperfections, such as inhomogeneities in the B and B fields.

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Cardiovascular disease (CVD) is the leading single cause of morbidity and mortality, causing over 17. 9 million deaths worldwide per year with associated costs of over $800 billion. Improving prevention, diagnosis, and treatment of CVD is therefore a global priority.

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The assessment of potential radon-hazardous environments is nowadays a critical issue in planning, monitoring, and developing appropriate mitigation strategies. Although some geological structures (e.g.

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