Publications by authors named "Chiara Benussi"
Objective: To assess whether exposure to non-invasive brain stimulation with transcranial alternating current stimulation at γ frequency (γ-tACS) applied over Pz (an area overlying the medial parietal cortex and the precuneus) can improve memory and modulate cholinergic transmission in mild cognitive impairment due to Alzheimer's disease (MCI-AD).
Methods: In this randomized, double-blind, sham controlled, crossover pilot study, participants were assigned to a single 60 min treatment with exposure to γ-tACS over Pz or sham tACS. Each subject underwent a clinical evaluation including assessment of episodic memory pre- and post-γ-tACS or sham stimulation.
Article Synopsis
- The study aimed to understand the relationship between genetic expansions, age at onset, and syndromic differences in frontotemporal lobar degeneration (FTLD) using a large European sample.
- Researchers found that pathogenic expansions were more common in patients with behavioral variant frontotemporal dementia (bvFTD) compared to primary progressive aphasia (PPA), and there were notable differences based on genetic ancestry.
- The findings suggest a link between genetic factors, ancestry, and the development of bvFTD, highlighting the complexity of genetic risk associated with this condition.