Publications by authors named "Chiaki Kubara"
Background: Posterior reversible encephalopathy syndrome (PRES) is known as a transfusion-related complication with typically favorable prognosis and no report fatalities. Pathological evaluation of PRES is also scarce.
Case Report: An 88-year-old female with myelodysplastic syndromes (MDS) attended our hospital because of a compression fracture and chronic heart failure with chronic anemia.
Article Synopsis
- * Initial tests for leukemia-related chimeric genes were negative, but karyotyping revealed an inversion in chromosome 16, which led to further analysis confirming the CBFB::MYH11 fusion gene through advanced techniques like FISH and RNA sequencing.
- * This case demonstrates a rare subtype of the CBFB::MYH11 fusion gene that can result in false-negative findings with standard screening, highlighting the importance of using modified PCR primers, FISH, and RNA sequencing for accurate diagnosis.