Publications by authors named "Chiaki Asahara"
J Agric Food Chem
September 2017
Article Synopsis
- FLP (flupyrimin) is a new insecticide developed by Meiji Seika Pharma that is effective against imidacloprid-resistant rice pests and is safe for pollinators.
- FLP acts as a nicotinic antagonist in cockroaches and shows selective binding to different subtypes of nicotinic acetylcholine receptors, including a receptor similar to that of imidacloprid.
- The research also explores the structure-activity relationships of FLP analogues, linking their pharmacophore properties to high receptor affinity and highlighting how its binding differs from imidacloprid's mechanism.
