MANAGEMENT OF A FATAL OUTBREAK OF STRONGYLOIDIASIS IN A CAPTIVE POPULATION OF PANTHER CHAMELEONS () WITH IVERMECTIN.

An outbreak of the nematode sp. occurred in a population of 18 male and 29 female panther chameleons () at the Singapore Zoo. The parasite was first detected in one individual during routine microscopic examination of feces using the direct examination and magnesium sulfate flotation methods.

MANAGEMENT OF IN THE HERPETOLOGICAL COLLECTION AT THE SINGAPORE ZOO.

Amebiasis caused by is an important disease in reptile collections, causing severe morbidity and mortality. Surveillance of the parasite at the Singapore Zoo was carried out over a 4-yr period by PCR testing on reptiles that presented with lethargy and enteritis for disease investigation. Asymptomatic reptiles sharing the same enclosures as positive individuals were also tested as part of outbreak investigation.

Population distribution and causes of mortality of smooth-coated otters, , in Singapore.

Smooth-coated otters () were transient in Singapore before one resident family group was observed in 1998, presumably having recolonized from Peninsular Malaysia. A population survey in 2017 revealed a minimum of 11 groups and 79 individuals. Since then, movements of otter groups within urban areas have led to increasing numbers of human-otter encounters, including conflicts.

Systemic and Cardiac Amyloidosis in Captive Celebes Crested Macaques (Macacanigra).

Systemic amyloidosis has been described in many animals and the most common form is reactive systemic AA amyloidosis. However, cardiac amyloidosis leading to heart failure is rare in animals. We now describe systemic and cardiac amyloidosis in two captive endangered Celebes crested macaques (Macaca nigra) at the Singapore Zoo.

Management of Entamoeba histolytica in the non-human primates at the Singapore Zoo.

Amebic dysentery caused by Entamoeba histolytica accounts for significant morbidity in the non-human primates (NHP) at the Singapore Zoo. This includes the animals in the collection as well as a sizeable free-roaming wild crab-eating macaque (Macaca fascicularis) population. The disease is of great concern because of its zoonotic potential.

Fatal Septicemia and Mastitis in Wild Sunda Colugos (Sunda Flying Lemurs; ) in Singapore.

Two free-ranging female Sunda colugos (Sunda flying lemur; ) were found dead in Singapore in November 2018 and February 2019. Septicemia and mastitis were diagnosed in both animals on postmortem examination. Infectious diseases have not previously been established as a cause of death in wild Sunda colugos.

First Report of Co-invasion by the Reptile Nematode Ozolaimus megatyphlon (Nematoda: Pharyngodonidae) with Invasive Green Iguanas (Iguana iguana) in the Asia-Pacific.

Purpose: Co-invasion of naïve ecosystems by non-native parasites is a serious threat to global biodiversity, though such events are difficult to detect early in the invasion process. Green iguanas (Iguana iguana) are an emerging invasive species and have colonised several countries in the Asia-Pacific. A survey was undertaken to determine whether parasites of the green iguana had co-invaded naïve ecosystems with their introduced host.

Intralesional methylprednisolone injection as an adjunct treatment for peri-cloacal pyogranuloma in an African penguin (Spheniscus demersus).

An African penguin (Spheniscus demersus) presented with a large peri-cloacal mass. The mass was diagnosed as a pyogranuloma histologically, with multifocal to coalescing inflammatory responses in the subcutis and keratinized simple stratified squamous epithelium overlying the surface. The patient was prescribed 125 mg/kg oral clavulanic acid/amoxycillin twice a day and 20 mg/kg oral terbinafine once a day for 14 days, but there was no change in the size of the mass 4 days after therapy, so a decision was made to administer 1 mg/kg of intralesional methylprednisolone.

The use of a 3D-printed prosthesis in a Great Hornbill (Buceros bicornis) with squamous cell carcinoma of the casque.

The advent of new technologies in medical imaging and 3D printing in recent years has made customization of surgical tools and implants more accessible, revolutionizing many surgical fields. In many human diseases, these implants have led to superior surgical outcomes and greatly improved patients' quality of life. Thus, it is of great interest to apply these technologies to the treatment of animal diseases.

Tick-crocodilian interactions: a review, with the first record of tick (Acari: Ixodidae) infestation in the saltwater crocodile (Crocodylus porosus), and a concise host-parasite index.

Interactions between ticks and crocodilians (crocodiles, alligators, caiman, and gharials) are poorly studied but may have significant bearing on the ecology and health of these reptiles. The first record of tick infestation of the saltwater crocodile (Crocodylus porosus) is reported along with the first case of infestation by Amblyomma cordiferum on Cuvier's dwarf caiman (Paleosuchus palpebrosus). A review is also provided of tick-crocodilian interactions with a concise host-parasite index.

Canine Parvovirus-2c (CPV-2c) Infection in Wild Asian Palm Civets () in Singapore.

We report pathogenic feline parvovirus and canine parvovirus-2c infection in wild Asian palm civets (), as demonstrated by histopathology and immunohistochemistry findings of parvoviral enteropathy. We performed molecular characterization and phylogeny studies to obtain an improved understanding of disease transmission dynamics between domestic and wild carnivores.

Correction to: The first authenticated record of the pangolin tick Amblyomma javanense (Acari: Ixodidae) in Singapore, with notes on its biology and conservation.

Due to an unfortunate turn of events, the surname of the third author appeared incorrectly in the original publication as it should have read Douay. The original article has been corrected, and the proper representation of the authors' names and their affiliation is also listed here.

The first authenticated record of the pangolin tick Amblyomma javanense (Acari: Ixodidae) in Singapore, with notes on its biology and conservation.

The first authenticated record of the co-endangered pangolin tick (Amblyomma javanense) is reported from the Republic of Singapore, based on specimens of males and females collected from the Sunda pangolin (Manis javanica). The biology of the species is reviewed and steps for its conservation are outlined to ensure its continued survival across its range.

Identification of possible nutritional and stress risk factors in the development of marmoset wasting syndrome.

Marmoset wasting syndrome (MWS) describes a series of symptoms in callitrichids that lead to general weakness and a failure to thrive in captive conditions such as zoological institutions. Though the cause of MWS has not been identified, the majority of hypotheses are linked to deficiencies of specific nutrients and increased stress levels. Questionnaires were sent to zoos requesting information on diets and housing of currently living and dead callitrichids before their deaths, as well as their postmortem reports.

Severe visceral pentastomiasis in an oriental small-clawed otter with functional thyroid carcinoma.

In January 2016, a 20-year-old female oriental small-clawed otter (Aonyx cinereus) from Night Safari in Singapore was euthanized and diagnosed with a thyroid gland carcinoma. Postmortem examination and histology also revealed metastasis to the regional lymph nodes and severe visceral pentastomiasis. Grossly, the lymph nodes were infested, and encapsulation was observed on the visceral serosal surface.

A nutritional nonalcoholic steatohepatitis minipig model.

Background And Aims: The objective of this study was to elucidate whether a Western diet was associated with nonalcoholic steatohepatitis (NASH), and the relationship between NASH, autophagy and endoplasmic reticulum (ER) stress.

Methods: Four-month-old Lee-Sung minipigs were randomly assigned to two groups: control diet (C) and Western diet (W), for a 5-month experimental period.

Results: Feeding a Western diet produced a body composition with more fat, less lean and a greater liver weight.

Interactions of host IL-6 and IFN-gamma and cancer-derived TGF-beta1 on MHC molecule expression during tumor spontaneous regression.

Many tumors down-regulate major histocompatibility complex (MHC) antigen expression to evade host immune surveillance. However, there are very few in vivo models to study MHC antigen expression during tumor spontaneous regression. In addition, the roles of transforming growth factor betal (TGF-beta1), interferon gamma (IFN-gamma), and interleukin (IL)-6 in modulating MHC antigen expression are ill understood.

Use of chemical ablation with trichloroacetic acid to treat eyelid apocrine hidrocystomas in a cat.

Case Description: A 7-year-old Persian cat was evaluated for recurrence of multiple cystic periocular masses. A number of cyst-like lesions had been resected from the left eyelids 18 months earlier, with lesions recurring within 6 months after surgery. The cat had blepharospasm and signs of discomfort following rupture of the largest cyst the day prior to examination.