Publications by authors named "Chia-Yun Hsieh"

Transition metal dichalcogenide (TMD) monolayers exhibit unique valleytronics properties due to the dependency of the coupled valley and spin state at the hexagonal corner of the first Brillouin zone. Precisely controlling valley spin-polarization via manipulating the electron population enables its application in valley-based memory or quantum technologies. This study uncovered the uncompensated spins of the antiferromagnetic nickel oxide (NiO) serving as the ferromagnetic (FM) order to induce valley spin-polarization in molybdenum disulfide (MoS) monolayers via the magnetic proximity effect (MPE).

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Background: Rifampin is a potent chemoprophylactic antibiotic for Haemophilus influenzae infection, and the resistance rate in H. influenzae is low. In this study, we assessed rifampin resistance-related genetic variations in H.

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Article Synopsis
  • The study investigates the link between exposure to airborne heavy metals, specifically arsenic, cadmium, mercury, and lead, and the development of autism spectrum disorder (ASD) in a large cohort of over 168,000 live births in Taichung between 2004 and 2011.
  • A positive correlation was found between mercury exposure and increased ASD risk, particularly noted at 9 months post-birth, with heightened risk during specific postnatal weeks for low birth weight infants.
  • The findings suggest that exposure to certain heavy metals, especially mercury, during critical developmental periods may significantly impact ASD incidence, particularly in infants with low birth weight.
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Isatis indigotica Fort. (family Cruciferae), is an herb widely used in traditional herbal medicine and its dried leave was named "ISATIDIS FOLIUM". Baphicacanthus cusia (Ness) Bremek.

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Article Synopsis
  • - The study investigates how exposure to fine particulate matter (PM) during pregnancy and early infancy affects the development of allergic rhinitis (AR) in children, aiming to outline critical vulnerable periods to mitigate risks.
  • - An analysis of data from a large cohort of 140,911 infants in Taichung, Taiwan revealed that around 33.55% developed AR, typically diagnosed around age 3; increased PM exposure during late pregnancy to the first year of life correlated significantly with higher AR risk.
  • - Results indicate that both prenatal and postnatal PM exposure contributes to AR development, with the most vulnerable periods identified as late gestation and the first year after birth, suggesting a need for further research to reinforce these findings.
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Background: Asthma is the most common chronic allergic disease in children; it affects more than 300 million people worldwide. Information on the association between exposure to ambient heavy metals and incidence of pediatric asthma is limited.

Objective: We sought to evaluate the effects of heavy metals during pregnancy and infancy periods with asthma and identify a sensitive time window, clarifying the effect of ambient heavy metals on lung development.

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Mild hypothermia has promising effects in the treatment of acute brain insults and also affects cell cycle progression. Mitochondrial dynamics, fusion and fission, are changed along with the cell cycle and disrupted in neurodegenerative diseases, including Parkinson's disease (PD). However, the effects of hypothermia on aberrant mitochondrial dynamics in PD remain unknown.

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The majority of patients with hydrocephalus are dependent on ventriculoperitoneal shunts for diversion of excess cerebrospinal fluid. Unfortunately, these shunts are failure-prone and over half of all life-threatening pediatric failures are caused by obstruction of the ventricular catheter by the brain's resident immune cells, reactive microglia and astrocytes. Poly(2-hydroxyethyl methacrylate) (PHEMA) hydrogels are widely used for biomedical implants.

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Mitochondrial dysfunction and oxidative stress are involved in the pathogenesis of Parkinson's disease (PD). Mitochondrial morphology is dynamic and precisely regulated by the mitochondrial fission and fusion machinery. Aberrant mitochondrial fragmentation controlled by the mitochondrial fission protein, dynamin-related protein 1 (Drp1), may result in cell death.

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While superhydrophobic nanostructured surfaces have been shown to promote condensation heat transfer, the successful implementation of these coatings relies on the development of scalable manufacturing strategies as well as continued research into the fundamental physical mechanisms of enhancement. This work demonstrates the fabrication and characterization of superhydrophobic coatings using a simple scalable nanofabrication technique based on self-assembly of the Tobacco mosaic virus (TMV) combined with initiated chemical vapor deposition. TMV biotemplating is compatible with a wide range of surface materials and applicable over large areas and complex geometries without the use of any power or heat.

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Purpose: To compare the bacteriostatic effects, corneal cytotoxicity, and ability to seal corneal incisions among fibrin glue and 2 commercially available cyanoacrylate derivatives: N-butyl cyanoacrylate and methoxypropyl cyanoacrylate.

Methods: The bacteriostatic activities of these tissue glues were verified by measuring the zones of bacterial growth inhibition surrounding the adhesive droplets on agar plates inoculated with Staphylococcus aureus, Streptococcus pneumoniae, Pseudomonas aeruginosa, Escherichia coli, or Mycobacterium chelonae. Corneal cytotoxicity was tested by a direct contact method by using cultured bovine corneal epithelial cells, keratocytes, and corneal endothelial cells challenged with droplets of adhesives.

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