Aggregation-induced emission silence-mediated pathogen detection using a rapidly degradable nanographene-embedded polymersome.

Typical pathogen detection processes are time-consuming and require expensive equipment and professional operators, limiting their practical applicability. Developing a rapid and easy-to-read method of accurately sensing pathogenic bacteria is critical for reducing the spread and risk of infection in high-risk areas. Herein, the synthesis of nanographene (nanoG) that exhibits aggregation-induced emission (AIE) is described.

Investigation of Mechanochromic Luminescence of Pyrene-based Aggregation-Induced Emission Luminogens: Correlation between Molecular Packing and Luminescence Behavior.

To better understand the correlation between molecular structure and optical properties such as aggregation-induced emission (AIE) and mechanochromic luminescence (MCL) emission, two new pyrene-based derivatives with substitutions at the 4- and 5-positions (1HH) and at the 4-, 5-, 9-, and 10-positions (2HH) were designed and synthesized. Cyano groups were introduced at the periphery of the synthesized compounds (1HCN, 1OCN, 1BCN, 2HCN, 2OCN, and 2BCN) to investigate the influence of these groups on the emission properties of the pyrene derivatives both in solution and in the solid state. The fluorescence emission performance of these compounds in water/acetone mixtures was simultaneously studied, revealing outstanding aggregation-induced emission properties.

An Efficient ECG Classification System Using Resource-Saving Architecture and Random Forest.

This paper presents a resource-saving system to extract a few important features of electrocardiogram (ECG) signals. In addition, real-time classifiers are proposed as well to classify different types of arrhythmias via these features. The proposed feature extraction system is based on two delta-sigma modulators adopting 250 Hz sampling rate and three wave detection algorithms to analyze outputs of the modulators.

Identification of essential histidine residues in a recombinant alpha-amylase of thermophilic and alkaliphilic Bacillus sp. strain TS-23.

To understand the structure-function relationships of a truncated Bacillus sp. strain TS-23 alpha-amylase, each of His-137, His-191, His-239, His-269, His-305, His-323, His-361, His-436, and His-475 was replaced with leucine. The molecular masses of the purified wild-type and mutant enzymes were approximately 54 kDa.