Publications by authors named "Chia-Yi Yen"

Monolithic phosphor-free two-color gallium nitride (GaN)-based white light emitting diodes (LED) have the potential to replace current phosphor-based GaN white LEDs due to their low cost and long life cycle. Unfortunately, the growth of high indium content indium gallium nitride (InGaN)/GaN quantum dot and reported LED's color rendering index (CRI) are still problematic. Here, we use flip-chip technology to fabricate an upside down monolithic two-color phosphor-free LED with four grown layers of high indium quantum dots on top of the three grown layers of lower indium quantum wells separated by a GaN tunneling barrier layer.

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The tumor-homing ability of monocytes renders them a potential cellular delivery system for alternative cancer therapies, although their migratory ability can be impaired following reagent uptake. Approaches that enhance monocyte tumor homing and promote their migration will improve the clinical value of these cells as cellular carriers. Previous studies have shown that irradiation (IR) can promote macrophage aggregation in hypoxic regions.

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Overcoming limitations often experienced in nanomedicine delivery toward hypoxia regions of malignant tumors remains a great challenge. In this study, a promising modality for active hypoxia drug delivery was developed by adopting tumortropic monocytes/macrophages as a cellular vehicle for co-delivery of echogenic polymer/C5F12 bubbles and doxorubicin-loaded polymer vesicles. Through the remote-controlled focused ultrasound (FUS)-triggered drug liberation, therapeutic monocytes show prominent capability of inducing apoptosis of cancer cells.

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This follow-up study provided an evaluation on threshold operation criteria of biostimulation in immobilized cell systems (ICSs) with Aeromonas hydrophila onto packing materials Porites corals. Essential nutrients in appropriate flow rate for biostimulation were inevitably required to maintain maximum attached cell population for cost-effective biodecolorization. With the method of "graphical reconstruction", the most economically feasible strategy of medium stimulation for color removal was quantitatively revealed.

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This study tended to evaluate threshold operation criteria of biostimulation for optimal biodecolorization in immobilized-cell systems (ICSs) using Porites corals as packing matrices. Indigenous Aeromonas hydrophila with high efficiency for decolorization isolated from Northeast Taiwan was used for study. As maximal treatment performance of ICS could only be achieved with maximal absorbed biomass with highest color removal capability.

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This novel comparative study tended to disclose how the molecular structures present in seven azo dyes including two types of azo dyes (i.e., naphthol type azo dyes--Reactive Black 5 (RB 5), Reactive Blue 171 (RB 171), Reactive Green 19 (RG19), Reactive Red 198 (RR198), Reactive Red 141 (RR141), and non-naphthol type azo dyes--Direct Yellow 86 (DY86), Reactive Yellow 84 (RY84)) affected color removal capability of Aeromonas hydrophila.

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This study attempted to combine chemostat pulse technique (CPT) and dose-mortality assessment in pursuit of quantitative rankings of toxicity of model aromatic amines (MAAs) in the presence of diazo dye reactive red 141 (or Evercion Red H-E7B; RR141) upon Aeromonas hydrophila. As known, bacterial decolorization performance of azo dyes is directly dependent upon both the characteristics of biochemical reactivity and biotoxicity of dyes and related aromatic amines towards color removal. Thus, the findings herein indicated that the relative toxicity series of MAAs were (1) ortho>para>MAA-free control>meta position (for isomeric aminophenols); (2) -OH>-SO(3)H>MAA-free control (-NH(2) at ortho position); (3) -COOH>MAA-free control>-OH (-NH(2) at meta position) through the CPT at 200mg/L MAAs.

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