Publications by authors named "Chia-Tai Liu"
Background: A reliable and simple test for the detection of malaria parasite is crucial in providing effective treatment and therapeutic follow-up, especially in malaria elimination programmes. A comparison of four methods, including nested polymerase chain reaction (PCR) and loop-mediated isothermal amplification (LAMP) were used for the malaria diagnosis and treatment follow-up in São Tomé and Príncipe, during a successful pre-elimination campaign.
Method: During the period September to November 2009, blood samples from 128 children (five to 14 years old) with temperature ≥38°C (tympanic) in the District of Agua Grande were examined using four different methods, i.
Article Synopsis
- Plasmodium falciparum was a major cause of malaria in São Tomé, with high incidence rates before 2004, but effective malaria control measures implemented since then led to a 95% reduction in morbidity and mortality by 2008.
- The integrated control program included strategies such as indoor residual spraying, insecticide-treated nets, and early diagnosis with artemisinin-based combination therapy, significantly lowering malaria incidence rates over the years.
- Despite these successes, asymptomatic malaria carriers remained a challenge, with only half of them receiving effective treatment, highlighting the need for ongoing control measures to prevent future outbreaks.
Background: Plasmodium falciparum is the major species responsible for malaria transmission on the island of Príncipe, in the Republic of São Tomé and Príncipe (STP). Indoor residual spraying (IRS) has been intensively deployed on the island, since 2003. Other measures included intermittent preventive therapy (IPT), since 2004, as well as artemisinin-based therapy (ACT) and long-lasting insecticidal nets (LLINs) from 2005.
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