Combined aerobic and resistance training improves physical and executive functions in women with systemic lupus erythematosus.

Objectives: Exercise is considered as an adjuvant therapeutic modality to alleviate symptoms of several rheumatic diseases. However, data regarding the benefits of exercise to patients with systemic lupus erythematosus (SLE) are relatively scant.

Methods: This study aimed to assess the effects of regular, moderate-intensity, aerobic exercise combined with resistance training on women with SLE who had no regular exercise.

The Activating Transcription Factor 3 () Homozygous Knockout Mice Exhibit Enhanced Conditioned Fear and Down Regulation of Hippocampal .

The genetic and molecular basis underlying fear memory formation is a key theme in anxiety disorder research. Because activating transcription factor 3 () is induced under stress conditions and is highly expressed in the hippocampus, we hypothesize that plays a role in fear memory formation. We used fear conditioning and various other paradigms to test knockout mice and study the role of in processing fear memory.