This single-center retrospective study enrolled 22 patients, who were divided into two groups: those who underwent wide excision (group A) and those who did not (group B). Group A included 13 patients, and group B included 9. Most of the cases fell into early stages (I and II).
View Article and Find Full Text PDFObjective: To evaluate the feasibility and effectiveness of a novel tissue-plug modification of the pectoralis major myocutaneous flap for repairing intractable pharyngocutaneous fistulas, especially in difficult-to-access defects.
Materials And Methods: The novel technique involved designing a tissue-plug modification of pectoralis major myocutaneous flap and suspension sutures. Cadaver studies were performed to refine the surgical method before clinical application.
Purpose: To determine the mutation spectrum of the connexin 26 gene among 324 Taiwanese patients with prelingual deafness and the carrier rate of gene mutation in another 432 unrelated control subjects.
Methods: The coding region of the connexin 26 gene was sequenced in both directions to detect mutation in all 756 samples.
Results: Among the 756 samples tested, 21 connexin 26 variants were detected, including 7 novel ones.