Publications by authors named "Chia Wei Kong"
Article Synopsis
- Tissue-resident natural killer (trNK) cells in the lungs may play a significant role in respiratory immunity, especially in chronic lung diseases like COPD, but their exact functions are not well understood.
- Researchers conducted a study on mice exposed to cigarette smoke to mimic COPD and analyzed trNK cell behaviors in both mouse and human lung tissues when infected with influenza A virus.
- Findings revealed that specific NK cell populations, especially CD49a NK cells, exhibited altered functions during COPD, showing increased activity when confronted with viral infections, which could lead to heightened inflammation in COPD patients.
More than a third of patients hospitalised for acute exacerbation of COPD are readmitted to hospital within 90 days. Healthcare professionals and service providers are expected to collaboratively drive efforts to improve hospital readmission rates, which can be challenging due to the lack of clear consensus and guidelines on how best to predict and prevent readmissions. This review identifies these risk factors, highlighting the contribution of multimorbidity, frailty and poor socioeconomic status.
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