Is the delayed surgery after neoadjuvant chemoradiation beneficial for locally advanced rectal cancer?

Background: Neoadjuvant treatment with radiotherapy and chemotherapy is the preferred regimen for locally advanced rectal cancer, aiming to increase resectability and decrease local recurrence.

Aim: To evaluate the benefits of delayed surgery after neoadjuvant chemoradiation in advanced rectal cancer regarding aspects of tumor response, survival and its deleterious effects.

Methods: Were treated 106 patients consecutively with locally advanced rectal adenocarcinoma.

Inflammatory bowel disease activity assessed by fecal calprotectin and lactoferrin: correlation with laboratory parameters, clinical, endoscopic and histological indexes.

Background: Research has shown that fecal biomarkers are useful to assess the activity of inflammatory bowel disease (IBD). The aim of the study is: to evaluate the efficacy of the fecal lactoferrin and calprotectin as indicators of inflammatory activity.

Findings: A total of 78 patients presenting inflammatory bowel disease were evaluated.

[Rectal and anal straining pressures in primigravidae].

Objective: This study intended to evaluate rectal and anal straining pressures in primigravidae, at simulated defecation.

Methods: The present study is based on 60 women from de Antenatal Care of Santa Casa de Misericórdia - São Paulo. Patients were divided into four groups of 15: a)

Control Group: nuligravidae; b) 1st trimester primigravidae; c) 2nd trimester primigravidae; d) 3rd trimester primigravidae.

[Surgical treatment of rectal prolapse by the Delorme technique and rectopexy].

Objective: Rectopexy is the most common technique used to correct rectal prolapse. Perineal procedures such as the Delorme technique and others are employed for older frail patients with significant comorbidity because of the higher recurrence rate. This study evaluated results of the Delorme technique and rectopexy.