Publications by authors named "Chi-Zhou Tu"
Org Biomol Chem
September 2024
Article Synopsis
- Researchers successfully created axially chiral C2-arylquinoline through an asymmetric reaction involving alkynes, using chiral phosphoric acid as a catalyst, achieving high yields and enantioselectivity.
- The study outlines a detailed reaction mechanism divided into key steps: hydrogen transfer, C-N bonding, annulation, and dehydration, with multiple potential pathways for each step.
- Theoretical analyses, including QTAIM and IGMH, clarified the influence of weak intermolecular interactions and provided insights into enantioselectivity, with theoretical calculations aligning well with experimental outcomes.
