De novo motif discovery facilitates identification of interactions between transcription factors in Saccharomyces cerevisiae.

Motivation: Gene regulation involves complicated mechanisms such as cooperativity between a set of transcription factors (TFs). Previous studies have used target genes shared by two TFs as a clue to infer TF-TF interactions. However, this task remains challenging because the target genes with low binding affinity are frequently omitted by experimental data, especially when a single strict threshold is employed.

Predicting protein-protein interactions in unbalanced data using the primary structure of proteins.

Background: Elucidating protein-protein interactions (PPIs) is essential to constructing protein interaction networks and facilitating our understanding of the general principles of biological systems. Previous studies have revealed that interacting protein pairs can be predicted by their primary structure. Most of these approaches have achieved satisfactory performance on datasets comprising equal number of interacting and non-interacting protein pairs.

The 3D scanner for measuring body surface area: a simplified calculation in the Chinese adult.

Three-dimensional (3D) surface anthropometry enables us to extend the study to 3D geometry and morphology of mainly external human body tissues. A model is presented for estimation of human body surface area (BSA), which is identical in form to the one proposed in 1916 by DuBois and DuBois is presented. The purpose of this study is to measure BSA, using 3D scanner, and to derive a simple BSA estimation formula for the Chinese adults.