Publications by authors named "Chi-Yu Liu"

Article Synopsis
  • The study investigates how glycolysis affects cardiac fibroblast activation and cardiac fibrosis following a heart attack (myocardial infarction).
  • Daily injections of the glycolysis inhibitor 2-Deoxy-D-glucose (2-DG) were administered to mice after a heart attack, with various tests performed to assess heart function and fibrosis levels.
  • Results showed that 2-DG reduced the activation of cardiac fibroblasts and fibrosis, highlighting that inhibiting glycolysis could help mitigate damage after a heart attack.
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Article Synopsis
  • Mitochondrial fission in cardiac fibroblasts (CF) was studied to understand its effects on cell activation and mitochondrial health, particularly when stimulated by TGF-β1.
  • The research found that TGF-β1 treatment significantly increased mitochondrial fragmentation and fission-related protein expression while altering fusion proteins, which contributed to CF activation.
  • Inhibition of mitochondrial fission reduced the activation of CF and their glycolysis rate, highlighting the interplay between mitochondrial dynamics, reactive oxygen species, and the mitophagy process, particularly through the Pink1 pathway.
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Background: The clinical significance of influenza B is frequently overlooked, and reports on influenza B pneumonia in children are limited. Therefore, the clinical features of associated complications have rarely been reported. The aim of this study is to evaluate the clinical characteristics in pediatric patients with influenza B virus-associated pneumonia.

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We studied, numerically, the characteristics of the surface plasmon of a system consisting of several pair arrays of silver-shell nanocylinders. Effects from different numbers of pair arrays, illumination wavelengths, and the core refractive index of silver-shell nanocylinders are studied by using the finite-element method. Results show that the peak wavelengths shift to shorter wavelengths (blueshifted) when the number of pair arrays increases from three to six.

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