Publications by authors named "Chi-Hsien Wu"
Background: Multisystem inflammatory syndrome in children (MIS-C) is a novel disease associated with COVID-19. The COVID-19 epidemic peaked in May 2022 in Taiwan, and we encountered our first case of MIS-C in late May 2022. We aimed to present patients' clinical manifestations and identify risk factors for shock.
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- A significant rise in COVID-19 cases in Taiwan since April 2022 is particularly concerning for children, prompting an analysis of their clinical outcomes related to the Omicron variant.
- Among 339 hospitalized pediatric patients, common symptoms included fever (94.1%), with 6.5% classified as severe cases, highlighting the presence of serious complications such as encephalopathy and shock in vulnerable patients.
- Identified risk factors for severe COVID-19 included pre-existing congenital cardiovascular conditions, prolonged fever, oxygen desaturation, seizures, and elevated procalcitonin levels, indicating the need for vigilant monitoring and potential early interventions for affected children.
Background: In Taiwan, the prevalence of COVID-19 was low before April 2022. The low SARS-CoV-2 seroprevalence in the population of Taiwan provides an opportunity for comparison with fewer confounding factors than other populations globally. Cycle threshold (Ct) value is an easily accessible method for modeling SARS-CoV-2 dynamics.
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