Publications by authors named "Chi Won Shin"

Article Synopsis
  • The study aimed to analyze how methadone moves through and is cleared from the body in domestic ferrets after being given either through an intravenous (IV) or subcutaneous (SC) method.
  • Eight healthy adult ferrets were used in a crossover experiment where they received a dose of methadone, and blood samples were taken at various intervals to measure drug concentration.
  • Results showed that IV methadone had a high clearance rate and a large volume of distribution, while SC administration provided high bioavailability; however, the drug's effects only lasted for a limited time after both routes of administration.
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A 15-year-old intact male dachshund dog weighing 4.3 kg and a 5-year-old intact male mixed-breed dog weighing 13.6 kg were referred for examination because of paraparesis and facial paralysis, respectively.

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We demonstrate excitatory and inhibitory properties in a single heterostructure consisting of two quantum dots/graphene synaptic elements using linearly polarized monochromatic light. Perovskite quantum dots and PbS quantum dots were used to increase and decrease photocurrent weights, respectively. The polarization-dependent photocurrent was realized by adding a polarizer in the middle of the PbS quantum dots/graphene and perovskite quantum dots/graphene elements.

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This study was performed to evaluate the effect of intra-abdominal pressure (IAP) on intraocular pressure (IOP) in conscious dog models using a balloon technique to generate intra-abdominal hypertension. Six healthy dogs without ocular abnormalities were evaluated in this study. A balloon device was placed in the intra-abdominal cavity.

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Objective: To describe an approach for ethmoidal nerve block (E) and to compare the effects of a maxillary nerve block (M), E and their combination (M-E) on heart rate (HR), systolic (SAP), mean (MAP), diastolic (DAP) arterial pressures and respiratory rate (f) during nasal stimulation in dogs.

Study Design: Prospective, blinded, randomized, crossover placebo-controlled study.

Animals: Beagle dogs (five cadavers, nine live dogs), with a median (interquartile range) weight of 10.

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Objective: To evaluate an approach to the canine lumbar dorsal root ganglion (DRG), a significant contributor to the pain pathway, using new methylene blue staining.

Study Design: Prospective randomized study.

Animals: A total of three Beagle dog cadavers weighing 10.

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Objective: To evaluate the effect of intra-abdominal pressure (IAP) on plasma exogenous creatinine clearance in both conscious and anesthetized dog models using a balloon technique to generate intra-abdominal hypertension.

Design: Prospective, cross-over, experimental study.

Setting: University-based small animal research facility.

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Objective: To compare the effects of epidural injection of three volumes of lidocaine injected at the third (T3) or eleventh thoracic vertebra (T11) in conscious dogs to induce thoracic epidural anesthesia (TEA) and to measure the epidural dispersion of iohexol under similar conditions.

Study Design: Prospective crossover experiment.

Animals: A group of five Beagle dogs weighing 10.

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Objective: To evaluate endotracheal tube intracuff pressure (P) changes over time and the effect of these changes on air leak pressure (P).

Study Design: Prospective experimental study.

Animals: A group of nine healthy adult Beagle dogs.

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Objective: To evaluate a new balloon technique to induce intra-abdominal hypertension (IAH) and abdominal compartment syndrome in a conscious dog model, and to evaluate the effect of intra-abdominal pressure (IAP) on cardiovascular, respiratory, and arterial blood gas values in conscious dogs with IAH.

Design: Prospective, experimental study.

Setting: University-based small animal research facility.

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Objective: To determine the optimal endotracheal tube size in Beagle dogs using thoracic radiography.

Study Design: Prospective, randomized, crossover experimental study.

Animals: A total of eight healthy adult Beagle dogs.

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Somatic cell nuclear transfer allows generation of genetically identical animals using donor cells derived from animals with particular traits. To date, few studies have investigated whether or not these cloned dogs will show identical behavior patterns. To address this question, learning, memory and exploratory patterns were examined using six cloned dogs with identical nuclear genomes.

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