Publications by authors named "Chi Wei Mok"

Introduction: We presented the key findings from Singapore's Changi General Hospital Breast Centre's lymphedema surveillance strategy that used patients' reported symptoms, standard arm circumference measurements and clinical assessment in the diagnosis of breast cancer-related lymphedema (BCRL). Our secondary aim was to highlight and discuss important elements of a surveillance strategy that can be implemented to track this outcome measure of breast cancer treatment for future research.

Method: We conducted a cross-sectional study of 511 breast cancer patients to assess the prevalence of BCRL and its associated risk factors.

View Article and Find Full Text PDF
Article Synopsis
  • The study evaluated nipple and skin sensation after nipple-sparing mastectomy (NSM) to identify factors influencing these sensations.
  • A total of 460 patients were analyzed, with a mean age of 48.3, highlighting various surgical methods used (conventional, endoscopic, robotic) and their impact on sensation outcomes.
  • Results indicated that longer postoperative follow-up significantly improved nipple and skin sensations, particularly with specific incision types showing better outcomes.
View Article and Find Full Text PDF
Article Synopsis
  • The study compares outcomes of minimal access nipple-sparing mastectomy (R-NSM, E-NSM) to conventional nipple-sparing mastectomy (C-NSM) in terms of clinical results, patient satisfaction, and costs.
  • Both R-NSM and E-NSM showed better wound healing and patient-reported satisfaction with scars, although R-NSM incurred higher medical costs compared to the other two methods.
  • All three procedures demonstrated comparable safety concerning complications and oncological outcomes, indicating minimal access approaches are safe alternatives to conventional surgery.
View Article and Find Full Text PDF

Background: Breast reconstruction following oncological resection is becoming more common in recent years. In some ladies, implant reconstruction is not ideal due to significant implant visibility or palpability. Autologous reconstruction addresses the limitations of implant reconstruction but results in potential donor site morbidities.

View Article and Find Full Text PDF

Background: Surgical smoke generated through energy devices may present detrimental effects on individuals present in the operating room (OR). Despite the concerns possibly associated with surgical smoke, there may be no mandatory policies that suggest protective measures and limited firm standards are committed yet to address the same.

Aim: The aim of this paper is to present recommendations for surgeons and OR personnel by taking a consensus approach based on available literature and its interpretation by a multi-national panel of experts.

View Article and Find Full Text PDF

Background: We hypothesized that different BMI might have different impact on pre-operative MRI axillary lymph node (ALN) prediction accuracy and thereby subsequent surgical lymph node management. The aim of this study is to evaluate the effect of BMI on presentation, surgical treatment, and MRI performance characteristics of breast cancer with the main focus on ALN metastasis evaluation.

Methods: The medical records of patients with primary invasive breast cancer who had pre-operative breast MRI and underwent surgical resection were retrospectively reviewed.

View Article and Find Full Text PDF
Article Synopsis
  • Scientists are studying special gene changes (called PTVs) to see how they affect breast cancer in 8,852 Asian patients.
  • They found that having these gene changes is linked to more aggressive tumors, which are harder to treat.
  • Overall survival rates for patients with these gene changes were lower, suggesting that some genes might play a role in how long patients live after being diagnosed with breast cancer.
View Article and Find Full Text PDF

Background: In October 2019, surgeons from Changi General Hospital (CGH) Breast Centre delivered a series of health talk for its employees to assess the knowledge and perception of breast cancer screening and to improve the level of related knowledge amongst the institution's healthcare workers. This was to enable CGH, a healthcare provider to not only care for our patients, but also to look after its staff.

Methods: 141 hospital staff attended a 40-min talk followed by an open question and answer forum.

View Article and Find Full Text PDF

Rationale: Gynecomastia is a common benign breast disorder in men. Surgical management of gynecomastia includes that of a subcutaneous mastectomy with or without concurrent liposuction. Herein, the authors presented a case of complicated gynecomastia (gynecomastia with concurrent foreign body injection) which was successfully managed with an innovative technique that offered acceptable operative time, minimal complications, good recovery and satisfactory aesthetic outcome.

View Article and Find Full Text PDF

Background: Endoscopy-assisted breast surgery (EABS) performed through minimal axillary and/or peri-areolar incisions is a possible alternative to conventional breast surgery (CBS) for certain patients with breast cancer. In this study, we report the oncologic safety results of EABS compared with CBS.

Methods: Patients underwent EABS for breast cancer during the period June 2010 to March 2020 were collected from the EABS database from single institute, and another cohort of patients, who received CBS, were identified to determine the effectiveness and oncologic safety of EABS.

View Article and Find Full Text PDF

Background: The preliminary results of an innovative surgical technique, which incorporated single-port three-dimensional (3D) videoscope and instruments for endoscopic nipple-sparing mastectomy (E-NSM), were reported.

Methods: The medical records of patients who underwent single-port 3D E-NSM for breast cancer from August 2018 to September 2020 were analyzed, and the preliminary outcome of this procedure as well as the patient-reported aesthetic results are described in this article.

Results: The study enrolled 70 patients who received 80 procedures of single-port 3D E-NSM.

View Article and Find Full Text PDF

This article aims to provide a detailed description of the Singapore Breast Cancer Cohort (SGBCC), an ongoing multi-ethnic cohort established with the overarching goal to identify genetic markers for breast cancer risk, prognosis and treatment response, as well as to understand the ethnic differences in disease risk and outcome in an Asian setting. The cohort comprises of breast cancer patients aged 21 years and above from six public hospitals which diagnose and treat nearly 76% breast cancer cases in Singapore. Self-reported data on sociodemographic and lifestyle, reproductive risk factors, medical history and family history of breast or ovarian cancer is collected using a structured questionnaire.

View Article and Find Full Text PDF

Background: Robotic nipple sparing mastectomy (R-NSM), which uses the da Vinci surgical platform, could perform NSM and immediate breast reconstruction through a small and inconspicuous extra-mammary axillary or lateral chest incision. R-NSM was reported with extremely low nipple areolar complex (NAC) necrosis rate, good cosmetic results, and high patient satisfaction. However, there was little evidence available comparing the effectiveness and safety of R-NSM and conventional NSM (C-NSM) in the management of breast cancer.

View Article and Find Full Text PDF

Background: Endoscopic assisted breast surgery was associated with small and inconspicuous scar and endoscopic assisted breast conserving surgery (E-BCS) for breast cancer was increasingly performed as well. The clinical outcomes, learning curve analysis and patient reported cosmetic result of E-BCS for breast cancer were reported along with a review of the current literature.

Methods: A retrospective study analyzing the outcomes of E-BCS for breast cancer patients through an endoscopic breast surgery database in a single institution from June 2009 to May 2019 was performed and a literature review through Pubmed and Medline was conducted as well.

View Article and Find Full Text PDF

Surgical management of breast cancer has been evolving rapidly over the past 20-30 years. Prior to this, conventional surgical options were limited to either a mastectomy or breast conserving surgery. The demand for better aesthetic outcomes had driven the development of oncoplastic breast conserving surgery where glandular rearrangement or replacement coupled with thoughtfully placed incisions became the standard approach to breast conserving surgery.

View Article and Find Full Text PDF

Background: New surgical innovations of nipple-sparing mastectomy (NSM), such as endoscopic NSM (E-NSM) or robotic NSM (R-NSM), were emerging. However, there was a lack of evidence comparing the effectiveness and safety in the management of breast cancer.

Methods: A case-control comparison study was conducted for patients with breast cancer underwent E-NSM or R-NSM with immediate prosthesis breast reconstruction (IPBR) from July 2010 to February 2019 at a single institution to compare the clinical outcomes, learning curve, patient-reported cosmetic results, and medical cost.

View Article and Find Full Text PDF

Objectives: To achieve a consensus statement on robotic mastectomy.

Background: Robotic-assisted surgery has gained much attention especially the results of few case series reporting on the technical feasibility, safety and early oncologic outcomes of robotic-assisted mastectomy in a few centers worldwide. The aim of this consensus statement was to develop and provide standardized guidelines on robotic mastectomy based on consensus statement by a panel of experts from indications to outcome measures and indicators, thereby providing a valuable guide for breast surgeons worldwide.

View Article and Find Full Text PDF

Objectives: The aim of this study was to evaluate the diagnostic accuracy of breast MRI for detecting residual tumor and the tumor size whether it would be affected after neoadjuvant chemotherapy.

Methods: Total 109 patients with NAC and 682 patients without NAC were included in this retrospective study. Measurement of the largest diameter of tumors at pathology was chosen as gold standard and compared with preoperative breast MRI.

View Article and Find Full Text PDF
Article Synopsis
  • The study evaluated a new surgical technique using a single-port and 3D videoscope for endoscopic nipple-sparing mastectomy (E-NSM) on 11 breast cancer patients.
  • The average surgery time was about 182 minutes with minimal blood loss, and the procedure had a low rate of complications, with no severe issues like total nipple necrosis reported.
  • Patients expressed high satisfaction with cosmetic outcomes, with 93.3% pleased with their scars, and all would choose the same surgery again, suggesting E-NSM is effective and safe for breast cancer treatment.
View Article and Find Full Text PDF

To review current literature on the outcomes, techniques and trend of endoscopic-assisted breast surgery (EABS) in the management of breast cancer over a 20 years period Materials and Methods: Literature search was performed using PubMed/Medline database from 1st January 1998 to 31st December 2018 using the terms "endoscopy", "endoscopy-assisted", "breast cancer", "mastectomy" and "breast conserving surgery". Additional studies were also identified by reviewing references of relevant articles. Only case series and cohort studies were included in this review.

View Article and Find Full Text PDF

Intracystic papillary carcinoma of the breast is a rare subtype of breast cancer accounting for approximately 0.5-1% of all breast carcinomas. To the best of our knowledge, the occurrence of this rare subtype of breast cancer in the male is even lower with less than 20 cases reported in the English literature over the past 30 years.

View Article and Find Full Text PDF