Publications by authors named "Chi Keung Chan"

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  • * A systematic review will evaluate the impact of chatbot interventions on mental well-being in the Asian population, utilizing four electronic databases for data collection until December 2024.
  • * The study will include randomized controlled trials available in English or Chinese, assess bias and evidence quality, and share findings through peer-reviewed journals, funded by Tung Wah College.
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Trimeresurus albolabris (green pit viper) accounts for 95% of human venomous snakebites in Hong Kong and the Green Pit Viper antivenin has become the only antivenom available. Little is known about the impact of early antivenom administration on the duration of venom-induced coagulopathy. This retrospective study aimed to evaluate the impact of the door-to-antivenom time (DTAT) on the duration of such coagulopathy.

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  • The study investigated how methyl salicylate levels in the blood change after ingestion, aiming to identify peak serum concentrations and factors influencing these levels.
  • Researchers analyzed cases from the Hong Kong Poison Control Centre involving 41 patients, finding that the median time to peak concentration was 5.6 hours, with gastric aspiration and activated charcoal use being linked to lower peak levels.
  • Results suggest that the peak concentration of serum salicylate occurs slower than previously thought, indicating the need for ongoing monitoring in patients after ingestion.
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  • Cocaine when used with ethanol leads to the creation of cocaethylene, which has a longer effect; this study investigates the combined toxicity of these substances in Hong Kong.
  • A retrospective study analyzed 109 patients who had acute cocaine toxicities, confirming ethanol co-ingestion through blood tests in some cases.
  • Contrary to earlier studies, results indicated that using cocaine and ethanol together is linked to a lower risk of serious adverse outcomes compared to using cocaine alone.
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Background: Literature on systemic envenomation caused by tarantula bites, particularly from the Theraphosidae family, is relatively scarce. This case report provides a formal description of the first known instance of systemic envenomation caused by the Socotra Island Blue Baboon Tarantula (Monocentropus balfouri).

Case Report: In this case, a 23-year-old employee of an exotic pet shop suffered from perioral paresthesia, generalized muscle cramps, and rhabdomyolysis because of a Monocentropus balfouri bite.

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Social unrest, coupled with the outbreak of COVID-19, was a double-hit for Hong Kong in early 2020. Those stressful societal situations not only trigger negative emotions, such as anxiety and/or depression, but also consolidate a person's belief towards oneself (i.e.

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We report an uncommon case of cholinergic poisoning following an ingestion of wild mushrooms. Two middle-aged patients presented to the emergency unit with acute gastrointestinal symptoms including epigastric pain, vomiting and diarrhea, followed by miosis, palpitations and diaphoresis which were compatible with a cholinergic toxidrome. The patients volunteered a history of taking two tablespoons of cooked wild mushrooms collected in a country park.

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Objective: Metamfetamine use can cause serious complications or death. We aimed to derive and internally validate a clinical prediction score to predict major effect or death in acute metamfetamine toxicity.

Methods: We performed secondary analysis of 1,225 consecutive cases reported from all local public emergency departments to the Hong Kong Poison Information Centre between 1 January 2010 and 31 December 2019.

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Introduction: The positive relationship between future orientation and prosocial tendency has been consistently reported. However, the possible mechanism has not been examined yet. Previous research revealed the positive relationship between future orientation and meaning in life, as well as between meaning in life and prosocial tendency.

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Background: Early identification of patients at risk of seizure after acute tramadol overdose is crucial. Yet, current evidence has been inconclusive regarding the factors associated with the seizure. There is a lack of study on the Chinese population and the value of electrocardiogram (ECG) in risk prognostication has not been fully evaluated.

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  • * Research involved manipulating GLT-1 glutamate transporters and monitoring neuronal activity and glutamate levels using multielectrode arrays and specialized sensors, revealing significant changes to SB properties when GLT-1 was targeted.
  • * The study proposes that astrocytes provide a slow negative feedback mechanism to neuronal activities, suggesting that the interplay between neuronal excitation and astrocytic inhibition plays a crucial role in SB, with implications for understanding seizure-like conditions related to astrocyte dysfunction.
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  • - Members of collectivist cultures prioritize the happiness of their in-group (friends and family), while those from individualist cultures focus more on personal happiness, according to recent theory (Uchida et al., 2004).
  • - A study tested this concept by having participants recall kind acts towards close or distant individuals; results showed that recalling acts towards close ones improved emotional well-being significantly more for participants primed with collectivist cues (e.g., language) compared to individualist cues.
  • - Findings from two studies indicate that individuals with collectivist identities experience more positive emotions and less negative emotions when engaging in prosocial behavior towards close relationships versus strangers, especially in Hong Kong context.
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The lack of representative nasopharyngeal carcinoma (NPC) models has seriously hampered research on EBV carcinogenesis and preclinical studies in NPC. Here we report the successful growth of five NPC patient-derived xenografts (PDXs) from fifty-eight attempts of transplantation of NPC specimens into NOD/SCID mice. The take rates for primary and recurrent NPC are 4.

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Peer aggression and victimization are ubiquitous phenomena in schools which warrant the attention of educators and researchers. The high connection between aggression and victimization behooves researchers to look into how the comorbidity of them develops over time. The present study investigated the associations between aggression and victimization over 3 years in early adolescence and whether these associations are moderated by gender and teacher support.

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Background: We aimed to investigate the frequency of standard precautions (SPs) compliance and the factors affecting the compliance among nursing students (NSs).

Methods: A cross-sectional survey study guided by the health belief model was conducted in 2009. The study questionnaire is valid (content validity index, 0.

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The incidence of Clostridium difficile infection has increased rapidly during the past decade, increasing lengths of stays in the hospital, costs, and mortality rates. To address this increased incidence, we performed a retrospective case-control study using known risk factors to develop a tool to determine which patients are at risk for infection. Multivariate analysis generated a combination of risk factors associated with development of infection including prior admission, endoscopy within 30 days, cephalosporin/fluoroquinolone use, length of stay 7 days or longer, age 65 years or older, body mass index less than 25, and albumin level less than 2.

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The contribution of social context to school bullying was examined from the self-determination theory perspective in this longitudinal study of 536 adolescents from 3 secondary schools in Hong Kong. Latent class growth analysis of the student-reported data at 5 time points from grade 7 to grade 9 identified 4 groups of students: bullies (9.8%), victims (3.

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The motility of the Dictyostelium discoideum (DD) cell is studied by video microscopy when the cells are plated on top of an agar plate at different densities, n. It is found that the fluctuating kinetics of the cells can be divided into two normal directions: the cell's forward-moving direction and its normal direction. Along the forward-moving direction, the slope of the amplitude of fluctuation vs.

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Analyses examined academic achievement data across third through eighth grades (N = 26,474), comparing students identified as homeless or highly mobile (HHM) with other students in the federal free meal program (FM), reduced price meals (RM), or neither (General). Achievement was lower as a function of rising risk status (General > RM > FM > HHM). Achievement gaps appeared stable or widened between HHM students and lower risk groups.

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  • The study aimed to validate various assessment methods (serum paraquat level, SIPP, APACHE II, MSAPS II, and MSAPS IIe) for predicting mortality in cases of acute paraquat poisoning in an emergency department setting.
  • A total of 102 patients were analyzed, with results showing that serum paraquat level was the most effective predictor of mortality, outperforming other scoring systems like APACHE II.
  • The findings suggest that while serum paraquat levels are crucial for prognosis, MSAPS II and MSAPS IIe can still be useful in predicting outcomes when serum levels cannot be measured.
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We describe the use of dextrose 50% solution to differentiate naphthalene and paradichlorobenzene in the mothball float test. Its advantages over saturated salt solution are discussed.

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Longitudinal growth trajectories of reading and math achievement were studied in four primary school grade cohorts (GCs) of a large urban district to examine academic risk and resilience in homeless and highly mobile (H/HM) students. Initial achievement was assessed when student cohorts were in the second, third, fourth, and fifth grades, and again 12 and 18 months later. Achievement trajectories of H/HM students were compared to low-income but nonmobile students and all other tested students in the district, controlling for four well-established covariates of achievement: sex, ethnicity, attendance, and English language skills.

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We present studies of the resonance Raman and electronic luminescence spectra of the [Au(2)(dmpm)(3)](ClO(4))(2) (dmpm = bis(dimethylphosphine)methane) complex, including excitation into an intense band at 256 nm and into a weaker absorption system centered about approximately 300 nm. The resonance Raman spectra confirm the assignment of the 256 nm absorption band to a (1)(dsigma --> psigma) transition, a metal-metal-localized transition, in that nu(Au-Au) and overtones of it are strongly enhanced. A resonance Raman intensity analysis of the spectra associated with the 256 nm absorption band gives the ground-state and excited-state nu(Au-Au) stretching frequencies to be 79 and 165 cm(-1), respectively, and the excited-state Au-Au distance is calculated to decrease by about 0.

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