Publications by authors named "Chhagan Lal Birda"

Cytomegalovirus (CMV) and Epstein-Barr virus (EBV) are important causes of viral esophagitis mainly in immunocompromised individuals. Both viruses lead to development of focal ulcerations in the esophagus. While there have been rare case reports of esophagitis in immunocompetent individuals, there has not been a single reported case of coinfection with both CMV and EBV in an immunocompetent individual and presenting with diffuse esophageal ulceration.

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Article Synopsis
  • Budd-Chiari syndrome (BCS) involves blockage of the hepatic veins and is often linked to a condition that causes increased blood clotting.
  • Systemic amyloidosis is a disorder where misfolded proteins accumulate in the body, causing organ damage, and it typically leads to bleeding issues rather than clotting.
  • The case of a 40-year-old man illustrates how AL amyloidosis can lead to BCS, showing the importance of recognizing its varied and non-specific symptoms for accurate diagnosis.
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Hepaticojejunostomy is currently the best treatment for post-cholecystectomy biliary strictures. Laparoscopic repair has not gained popularity due to difficult reconstruction. We present case of 43-year-old-female with Bismuth type 2 stricture following laparoscopic converted open cholecystectomy with bile duct injury done elsewhere.

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The occurrence of diabetes mellitus (DM) in pancreatitis is being increasingly recognized lately. Diabetes can develop not only with chronic pancreatitis but even after the first episode of acute pancreatitis (AP). The incidence of diabetes after AP varies from 18% to 23% in 3 years and reaches up to 40% over 5 years.

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Background: Gastric varices (GVs) are conventionally managed with endoscopic cyanoacrylate (E-CYA) glue injection. Endoscopic ultrasound (EUS)-guided therapy using combination of coils and CYA glue (EUS-CG) is a relatively recent modality. There is limited data comparing the two techniques.

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Background: Timely intervention can alter outcome in patients of infected pancreatic necrosis (IPN) but lacks adequate biomarker. Role of serum procalcitonin (PCT) in the management of IPN is understudied, and hence, this study was planned.

Methodology: All patients of acute pancreatitis with IPN without prior intervention were included.

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Background And Aim: Liver involvement in celiac disease (CeD) is known but its various etiologies and the effect of gluten free diet (GFD) on it is understudied.

Methods: We searched PubMed, Medline and Embase databases from date of inception to March 7, 2022, to look for studies reporting on CeD and liver abnormalities. Pooled proportion of CeD patients with deranged transaminases, etiologies of various other liver diseases with CeD and the response to GFD were estimated.

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Introduction: Stricturing gastrointestinal tuberculosis (GITB) may result in persistent symptoms even after antitubercular therapy (ATT) and may require surgical intervention. Data on efficacy and safety of endoscopic dilatation for management GITB related strictures is scarce.

Methods: A retrospective analysis of database of patients who underwent endoscopic balloon dilatation for suspected or proven gastrointestinal tuberculosis was performed.

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Background: The prevalence of AP in pregnancy (APIP) is uncertain with varying reports of its impact on maternal and foetal outcomes.

Objectives: This study was aimed to find the prevalence of APIP and its effect on the maternal and foetal outcomes.

Search Strategy: Electronic databases were searched upto 31.

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Article Synopsis
  • The study analyzed 300 patients with necrotizing acute pancreatitis, focusing on organ failure (OF) and its impact on mortality.
  • Mortality was linked to the duration of OF rather than its initial onset, showing a significant increase as the pattern of organ failure became more severe (from single to sequential multiple organ failure).
  • The findings indicated that longer periods of organ failure and the presence of infected necrosis greatly increased the risk of death, highlighting the severity of sequential multiple organ failure.
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Oesophageal tuberculosis, an uncommon form of extrapulmonary tuberculosis, has been reported mainly as small case series and the literature is heterogeneous. A systematic review to characterize the clinical presentation, evaluation and management of oesophageal tuberculosis was performed. Electronic databases were searched with keywords: esophagus OR esophageal AND tuberculosis.

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Thrombotic Thrombocytopenic Purpura (TTP) is a poorly understood entity involving multiple organs and having grave prognosis if not treated promptly. Acute pancreatitis (AP) is a rare cause of TTP and TTP is also a rare complication of acute pancreatitis. TTP is induced in AP by poorly understood mechanism, which involves multiple pathways apart from only ADAMTS13 deficiency.

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Introduction: QTc interval is affected by many factors and prolongation of same may have prognostic significance. A significant number of patients admitted in medical emergency are acutely ill, have multiple comorbidities and are on medications, all of these factors might affect QTc interval and prognosis.

Materials And Methods: Single-center, prospective, observational study was carried out on 279 patients of different illnesses recruited from emergency medical services attached to the Department of Internal Medicine at Postgraduate Institute of Medical Education and Research, Chandigarh, India, a tertiary care hospital.

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