Publications by authors named "Cheyenne Belmont"
Article Synopsis
- Urinary tract infections (UTIs) are common bacterial infections, primarily caused by uropathogenic E. coli (UPEC), and are increasingly complicated by antimicrobial resistance (AMR).
- A study conducted in a San Francisco healthcare system from 2014-2019 found a high incidence of repeat UTIs among adults, particularly noting risk factors like male gender, diabetes, and previous UTIs.
- The research highlights the importance of understanding UTI recurrence and AMR trends to improve management strategies for preventing these infections.
Background: Urinary tract infections caused by extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli (ESBL-E. coli) may occur as outbreaks due to common-source exposures. Yet, it is currently unknown if they cluster geographically as would be expected as part of an outbreak.
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- A study conducted in San Francisco from January 2014 to March 2020 examined the spatial clustering of urinary tract infections caused by ESBL-producing bacteria among patients in a public healthcare system.
- Researchers found significant spatial clusters of individual ESBL- bacteriuria episodes, suggesting some outbreaks may occur due to common exposures.
- However, they discovered no geographical clustering of individuals with any type of ESBL- bacteriuria, indicating that these infections are more likely to recur in individuals than spread widely among different people.
Antimicrobial resistance in urinary tract infections (UTIs) is a major public health concern. This study aims to characterize the phenotypic and genetic basis of multidrug resistance (MDR) among expanded-spectrum cephalosporin-resistant (ESCR) uropathogenic Escherichia coli (UPEC) causing UTIs in California patient populations. Between February and October 2019, 577 ESCR UPEC isolates were collected from patients at 6 clinical laboratory sites across California.
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