Publications by authors named "Chew Jia Ming"
Aquat Toxicol
August 2024
Article Synopsis
- Phenytoin, an antiepileptic drug, was studied for its impact on the swimming behavior and reproductive ability of Japanese medaka fish, revealing significant behavioral abnormalities and reduced reproductive success.
- Abnormal swimming behaviors included imbalance and rotation, but these improved after discontinuing phenytoin exposure.
- The drug also suppressed key reproductive gene expressions related to the kisspeptin system, particularly kiss1, which likely contributed to the females' lack of interest in mating and reduced spawning.
