A bug tracking system (BTS) is a comprehensive data source for data-driven decision-making. Its various bug attributes can identify a BTS with ease. It results in unlabeled, fuzzy, and noisy bug reporting because some of these parameters, including severity and priority, are subjective and are instead chosen by the user's or developer's intuition rather than by adhering to a formal framework.
View Article and Find Full Text PDFAmong the challenges to the 21st-century health care industry, one that demands special mention is the transport of drugs/active pharmaceutical agents across the blood-brain barrier (BBB). The epithelial-like tight junctions within the brain capillary endothelium hinder the uptake of most pharmaceutical agents. With an aim to understand more deeply the intricacies of cell-penetrating and targeted peptides as a powerful tool for desirable biological activity, we provide a critical review of both CPP and homing/targeted peptides as intracellular drug delivery agents, especially across the blood-brain barrier (BBB).
View Article and Find Full Text PDFSuper-paramagnetic iron oxide nanoparticles (SPIONs/FeO) were synthesized in aqueous medium under a nitrogen atmosphere. These particles were made water-dispersible by cladding them with tannic acid (TA). The synthesized nanoparticles were characterized for their size and surface charge using HRTEM and zetasizer.
View Article and Find Full Text PDFCancer has been the leading cause of mortalities, with lung cancer contributing 18% to overall deaths. Non-small cell lung cancer (NSCLC) accounts for about 85% of all lung cancers. The primary form of therapy used to treat lung cancer still includes oral and systemic administration of drugs, radiotherapy, or chemotherapy.
View Article and Find Full Text PDFThe modern competition is moving quickly toward incorporating cutting-edge technological improvements to support Small and Medium Enterprises (SMEs) in enhancing their business models. Making decisions regarding implementing new technologies in SMEs is a challenging process driven by the continuous new advances in the technology industry. Important operational process decisions, such as organizational investment costs, technology acquisition, maintenance, customer experience, employee training for the proper use of each technology, reliability requirements, and security needs, must be made very carefully for such adoptions.
View Article and Find Full Text PDFThis paper presents a fuzzy inference method to investigate the impact of project-based assessment on the desirable outcomes by analyzing students creative and critical thinking, collaborative decision-making, and communication skills with realistic constraints and standards through theory and practical implementation in (a) course attainment and (b) on overall program attainment carried out in engineering discipline. This paper uses twelve specific parameters to capture program attainment parameters (PAPs). It proposes three main parameters to define various assessment system elements required for assessing course attainment parameters (CAPs), correlated with each other.
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