Quantification of Salivary Chromogranin A Levels during Routine Dental Procedures in Children: An Study.

Background: Routine dental procedures frequently involve invasive treatment, multiple injections, and the use of sharp, high-speed cutting instruments, and treatment is often extended over several visits, which are said to be stress-provoking events. Salivary chromogranin A (CgA) is a biomarker that can help clinicians evaluate and quantify the stress experienced by a child during these procedures.

Aim: To quantify the changes in salivary CgA levels in children before, during, and after routine dental procedures for multiple appointments.