Am J Gastroenterol
October 2024
Objective: Bulimia nervosa (BN) is associated with loss-of-control (LOC) eating episodes that frequently occur in response to negative emotions. According to recent neurocomputational models, this link could be explained by a failure to accurately update beliefs about the body in states of high arousal. Specifically, these interoceptive inference models suggest that under-relying on signals from one's body about sensory experience ("low sensory precision") and/or over-relying on previously held beliefs ("excessively precise priors") lead to inaccurate perception and maladaptive behaviors.
View Article and Find Full Text PDFFood banks provide an indispensable service to people experiencing severe food insecurity. Food banks source donations from across the food system; however, the food redistributed to clients across the developed world is nutritionally poor. This, together with the increasing prevalence of diet-related diseases and food insecurity, has prompted a focus on nutritional quality.
View Article and Find Full Text PDFThe 2022 global mpox outbreak raises questions about how this zoonotic disease established effective human-to-human transmission and its potential for further adaptation. The 2022 outbreak virus is related to an ongoing outbreak in Nigeria originally reported in 2017, but the evolutionary path linking the two remains unclear due to a lack of genomic data between 2018, when virus exportations from Nigeria were first recorded, and 2022, when the global mpox outbreak began. Here, 18 viral genomes obtained from patients across southern Nigeria in 2019-2020 reveal multiple lineages of monkeypox virus (MPXV) co-circulated in humans for several years before 2022, with progressive accumulation of mutations consistent with APOBEC3 activity over time.
View Article and Find Full Text PDFUnlabelled: Complex adaptive systems - such as critical infrastructures (CI) - are defined by their vast, multi-level interactions and emergent behaviors, but this elaborate web of interactions often conceals relationships. For instance, CI is often reduced to technological components, ignoring that social and ecological components are also embedded, leading to unintentional consequences from disturbance events. Analysis of CI as social-ecological-technological systems (SETS) can support integrated decision-making and increase infrastructure's capacity for resilience to climate change.
View Article and Find Full Text PDFAgricultural irrigation induces greenhouse gas emissions directly from soils or indirectly through the use of energy or construction of dams and irrigation infrastructure, while climate change affects irrigation demand, water availability and the greenhouse gas intensity of irrigation energy. Here, we present a scoping review to elaborate on these irrigation-climate linkages by synthesizing knowledge across different fields, emphasizing the growing role climate change may have in driving future irrigation expansion and reinforcing some of the positive feedbacks. This Review underscores the urgent need to promote and adopt sustainable irrigation, especially in regions dominated by strong, positive feedbacks.
View Article and Find Full Text PDFBackground: Sufficient, safe and nutritious food is unattainable for many people experiencing severe food insecurity, putting them at dietary risk. Food banks, a growing part of the charitable food system (CFS), are the main source of food relief in developed countries. Donations of surplus, unsalable food from supermarkets, producers and manufacturers is the main source of the food supply, and this can be unpredictable, insufficient and inappropriate.
View Article and Find Full Text PDFIn females, androgens contribute to ovarian diseases such as polycystic ovarian syndrome (PCOS), but their action is also crucial for ovarian physiology, i.e., follicular growth and estradiol (E2) synthesis during reproductive life, in interaction with the gonadotropins LH and FSH.
View Article and Find Full Text PDFFace masks are an effective and important tool to prevent the spread of COVID-19, including among children. However, occluding parts of the face can impact emotion recognition, which is fundamental to effective social interactions. Social distancing, stress, and changes to routines because of the pandemic have also altered the social landscape of children, with implications for social development.
View Article and Find Full Text PDFBackground: In the face of the COVID-19 pandemic, the Defence Science and Technology Laboratory (Dstl) and Defence Pathology combined to form the Defence Clinical Lab (DCL), an accredited (ISO/IEC 17025:2017) high-throughput SARS-CoV-2 PCR screening capability for military personnel.
Laboratory Structure And Resource: The DCL was modular in organisation, with laboratory modules and supporting functions combining to provide the accredited SARS-CoV-2 (envelope (E)-gene) PCR assay. The DCL was resourced by Dstl scientists and military clinicians and biomedical scientists.
Dementia is a stigmatizing condition requiring enhanced awareness and understanding. Churches are a trusted source of support for African Americans, a demographic disproportionately affected by dementia. However, many African American churches are not equipped with the knowledge and means to provide safe environments, resources, and spiritual and social support for their parishioners living with dementia and their families.
View Article and Find Full Text PDFPhospholipids (PLs) are amphiphilic molecules that were essential for life to become cellular. PLs have not only a key role in compartmentation as they are the main components of membrane, but they are also involved in cell signaling, cell metabolism, and even cell pathophysiology. Considered for a long time to simply be structural elements of membranes, phospholipids are increasingly being viewed as sensors of their environment and regulators of many metabolic processes.
View Article and Find Full Text PDFLippia alba is a phenotypically variable tropical shrub thought to comprise a young autopolyploid complex. Chromosome numbers in L. alba include 2n = 30, 38, 45, 60, and 90.
View Article and Find Full Text PDFThe purpose of this study was to identify the perceptions and attitudes of African American congregants toward dementia before and after attending a dementia-focused workshop. Six churches in Metropolitan Atlanta, Georgia, hosted the workshops. Attendees ( = 171) participated in a free association exercise to evaluate their perceptions and attitudes toward dementia.
View Article and Find Full Text PDFPublic Health Nurs
September 2020
Introduction: Alzheimer's disease and other dementia-related disorders are affecting the African-American community at alarming rates. African-American churches have traditionally been places of refuge where families go for support. However, many churches lack programs or resources to support families affected by dementia.
View Article and Find Full Text PDFMicrosatellite primers were developed in Lippia alba complex to better understanding the origins and evolution of the species. We sought to increase the numbers of available simple sequence repeat (SSR) markers. We performed low-coverage (~ twofold) genomic DNA sequencing of a diploid accession and generated a de novo assembly comprising 175,572 contigs.
View Article and Find Full Text PDFThis article comments on: . The story of promiscuous crucifers: origin and genome evolution of an invasive species, (Brassicaceae), and its relatives. Annals of Botany : 209–220.
View Article and Find Full Text PDFJ Autism Dev Disord
June 2019
Despite widespread clinical use of group-based social skills training (SST) for children with autism spectrum disorder (ASD), there remains a lack of follow-up data, generalisation effects, common definition of social skills, and teacher report data. This study evaluated the effectiveness of an 8-week SST intervention with a play component (unstructured versus semi-structured) for children with ASD across a range of social, behavioural and emotional measures. Forty-five children aged 8-12 years (M = 10.
View Article and Find Full Text PDFThe current study presents the initial validation of a new 20-item measure of heterophobia, a construct frequently discussed but inadequately researched in the literature on gay men's lives. This process included initial focus groups, exploratory and confirmatory national samples of gay men. The sample included measures of homophobia, rejection sensitivity, discrimination history, gay identity development, and social desirability to address convergent and discriminant validity.
View Article and Find Full Text PDFEnvironmental heat is a growing public health concern in cities. Urbanization and global climate change threaten to exacerbate heat as an already significant environmental cause of human morbidity and mortality. Despite increasing risk, very little is known regarding determinants of outdoor urban heat exposure.
View Article and Find Full Text PDFEnviron Sci Technol
September 2018
In the coming decades, ambient temperature increase from climate change threatens to reduce not only the availability of water but also the operational reliability of engineered water systems. Relatively little is known about how temperature stress can increasingly cause hardware components to fail, quality to be affected, and service outages to occur. Changes to the estimated-time-to-failure of major water system hardware and the probability of quality noncompliance were estimated for a modern potable water system that experiences hot summer temperatures, similar to Phoenix, AZ, and Las Vegas, NV.
View Article and Find Full Text PDFPremise Of The Study: Polyploidy has extensively shaped the evolution of plants, but the early stages of polyploidy are still poorly understood. The neoallopolyploid species Tragopogon mirus and T. miscellus are both characterized by widespread karyotypic variation, including frequent aneuploidy and intergenomic translocations.
View Article and Find Full Text PDFMany aspects of sex chromosome evolution are common to both plants and animals [1], but the process of Y chromosome degeneration, where genes on the Y become non-functional over time, may be much slower in plants due to purifying selection against deleterious mutations in the haploid gametophyte [2, 3]. Testing for differences in Y degeneration between the kingdoms has been hindered by the absence of accurate age estimates for plant sex chromosomes. Here, we used genome resequencing to estimate the spontaneous mutation rate and the age of the sex chromosomes in white campion (Silene latifolia).
View Article and Find Full Text PDFObjective: To assess the school breakfast program (SBP) in two schools with high Aboriginal student populations in rural Western Australia, their contribution to holistic support, nutritional health education and possibilities for improvement.
Methods: The operations and functioning of one regional and one remote SBP were assessed by stakeholder inquiry related to process and challenges, observations and documentary review. An intervention to increase health education, social interaction and learning about nutrition and food origins implemented in one school was assessed.