Effect of Fiber Reinforcement on the Flexural Strength of Long-Span, 3D-Printed, Interim Fixed Dental Prosthesis.

Purpose: To inspect the impact of polyethylene fiber (Ribbond) on the long-span, 3D-printed, interim fixed dental prosthesis regarding fracture strength.

Materials And Methods: A stainless steel platform was fabricated to replicate the partial edentulism for a maxillary four-unit fixed dental prosthesis. The prosthesis was fabricated by a Formlabs SLA 3D printer.

Conversion of a failing fixed implant prosthesis into an implant-retained overdenture: A clinical report.

Implants supporting a fixed prosthesis may fail leaving unfavorable implant distribution for a fixed prosthesis. This clinical report illustrates a treatment option for converting a failing fixed prosthesis into a mandibular complete overdenture by using a portion of the existing fixed implant prosthesis. The use of a resilient liner to retain a converted mandibular overdenture framework provided satisfactory results in the first year of clinical use.

Risk factors for reoperation following inguinal hernia repair: results from a cohort of patients from an integrated healthcare system.

Purpose: Inguinal hernia repair is one of the most common operations performed globally. Identification of risk factors that contribute to hernia recurrence following an index inguinal hernia repair, especially those that are modifiable, is of paramount importance. Therefore, we sought to investigate risk factors for reoperation following index inguinal hernia repair.

Use of polyvinyl siloxane to maintain peri-implant submucosal contours on removal of screw-retained implant-supported restorations.

When submucosal screw-retained implant-supported restorations are removed for a short period, the soft-tissue contours collapse, which can affect treatment expediency and patient comfort when restorations are reinserted. This technique involves the fabrication of a polyvinyl siloxane submucosal template to help mitigate the soft-tissue collapse and its potential sequelae. This method of maintaining peri-implant soft-tissue contours is achieved through a quick succession of steps: removing the screw-retained implant prosthesis, drying the soft tissue thoroughly, injecting light-bodied fast-set polyvinyl siloxane directly into the implant fixture of the internal connection implants and the screw channel for external connection implants together with the remaining submucosal areas, allowing the polyvinyl siloxane submucosal template to polymerize undisturbed, and removing it when ready to replace the prosthesis.

Evaluation of Fracture Resistance of Zirconia Modification/Polishing Around Implant Abutments.

Subcrestal placement of implants may have interproximal bone proximity issues that interfere with the submucosal contour of implant-supported zirconia restorations during delivery of the restorations. Modification of the mesial distal submucosal areas may be necessary to fully seat the restoration without impingement of the interproximal bone. Our aim was to determine if modification of submucosal cervical contour of implant supported zirconia-titanium base (Zi-Ti base) restorations resulted in a significant change in fracture strength compared with Zi-Ti base restorations without any modification near the cervical submucosal area.

Retrospective Comparison of Postinsertion Maintenances Between Conventional and 3D Printed Complete Dentures Fabricated in a Predoctoral Clinic.

Purpose: A retrospective study to analyze the clinical performance of 3D printed complete dentures in edentulous patients compared with conventional complete dentures regarding postinsertion visits and patient reported outcomes.

Material And Methods: Electronic charts were reviewed to analyze 420 (maxilla 270, mandible 150) heat-polymerized conventional complete dentures (CCD) inserted between July 1, 2015 and June 30, 2016 and 217 (maxilla 130, mandible 86) 3D printed complete dentures (PCD) inserted between July 1, 2017 and June 30, 2018. Number of remakes, number of postinsertion adjustments, type and number of repairs, and patient reported complications were compared between two types of complete dentures.

Evaluating the relationship between tooth color and enamel thickness, using twin flash photography, cross-polarization photography, and spectrophotometer.

Objectives: To understand (a) the effects of labial enamel on tooth color (b) relationship of color data taken by nonpolarized (NP), cross-polarization photography (CP), and spectrophotometry (SP).

Materials And Methods: Fifty extracted human maxillary incisors were coated with resin on their palatal surfaces. Their color was measured with NP, CP, and SP and their dimensions were scanned by an intraoral scanner.

Evaluation of Fracture Resistance of Varying Thicknesses of Zirconia Around Implant Abutment Cylinders.

Zirconia is becoming increasingly used as a restorative material for implant-supported restorations; however, information is lacking with respect to the minimum thickness of zirconia surrounding the implant components. The purpose of this study is to evaluate the resistance to fracture of different thicknesses of zirconia luted to implant components. Thirty cylinders of zirconia (Prettau, Zirkonzahn) with 13-mm height, designed with indented occlusal surface for loading, and varying wall thicknesses (0.

Genetic rescue of nonclassical ERα signaling normalizes energy balance in obese Erα-null mutant mice.

In addition to its role in reproduction, estradiol-17β is critical to the regulation of energy balance and body weight. Estrogen receptor α-null (Erα-/-) mutant mice develop an obese state characterized by decreased energy expenditure, decreased locomotion, increased adiposity, altered glucose homeostasis, and hyperleptinemia. Such features are reminiscent of the propensity of postmenopausal women to develop obesity and type 2 diabetes.

Progesterone receptor A (PRA) and PRB-independent effects of progesterone on gonadotropin-releasing hormone release.

Progesterone's (P4) negative feedback actions in the female reproductive axis are exerted in part by suppression of hypothalamic GnRH release. Here we show that P4 can inhibit GnRH release by a mechanism independent of a nuclear P4 receptor (PR(A/B)). Injections of P4, but not vehicle, allopregnanolone, or dexamethasone, acutely suppressed LH levels in both wild-type and P4 receptor knockout ovariectomized mice; pituitary responsiveness to GnRH was retained during P4 treatment, indicating a hypothalamic action.

p21-Activated kinase mediates rapid estradiol-negative feedback actions in the reproductive axis.

Nonclassical estrogen receptor alpha (ERalpha) signaling can mediate E(2) negative feedback actions in the reproductive axis; however, downstream pathways conveying these effects remain unclear. These studies tested the hypothesis that p21-activated kinase 1 (PAK1), a serine/threonine kinase rapidly activated by E(2) in nonneural cells, functions as a downstream node for E(2) signaling pathways in cells of the preoptic area, and it may thereby mediate E(2) negative feedback effects. Treatment of ovariectomized (OVX) rats with estradiol benzoate (EB) caused rapid and transient induction of phosphorylated PAK1 immunoreactivity in the medial preoptic nucleus (MPN) but not the arcuate nucleus.