Publications by authors named "Cheryl J Jones"
Meta-analysis of bone mineral density in adults with phenylketonuria.
Orphanet J Rare Dis
September 2024
Article Synopsis
- Lifelong management of phenylketonuria (PKU) involves medical nutrition therapy, where patients have to restrict dietary phenylalanine (Phe) and often use Phe-free or low-Phe protein substitutes, which may lead to low bone mineral density (BMD). !* -
- A meta-analysis was conducted to investigate BMD specifically in adults with PKU, analyzing data from 4097 individuals across 10 studies to assess BMD Z-scores and the prevalence of low BMD. !* -
- Results indicated that adults with PKU had significantly lower mean BMD Z-scores compared to age-matched controls, although still within acceptable ranges, with about 8% of individuals