Publications by authors named "Cheryl Barth"
Background: Whether vigorous exercise increases risk of ventricular arrhythmias for individuals diagnosed and treated for congenital long QT syndrome (LQTS) remains unknown.
Methods: The National Institutes of Health-funded LIVE-LQTS study (Lifestyle and Exercise in the Long QT Syndrome) prospectively enrolled individuals 8 to 60 years of age with phenotypic and/or genotypic LQTS from 37 sites in 5 countries from May 2015 to February 2019. Participants (or parents) answered physical activity and clinical events surveys every 6 months for 3 years with follow-up completed in February 2022.
Aims: The role of lay health workers in data collection for clinical and translational research studies is not well described. We explored lay health workers as data collectors in clinical and translational research studies. We also present several methods for examining their work, i.
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- The study investigates whether vigorous exercise increases the risk of ventricular arrhythmias and mortality in individuals with hypertrophic cardiomyopathy (HCM).
- Researchers enrolled 1,660 participants aged 8 to 60 with HCM or its genetic markers, categorizing them by their exercise levels (sedentary, moderate, vigorous).
- The primary outcomes included serious events like death and arrhythmias, with findings analyzed by an unbiased committee to evaluate the effects of exercise intensity on these health risks.
Background: The risks of sports participation for implantable cardioverter-defibrillator (ICD) patients are unknown.
Methods And Results: Athletes with ICDs (age, 10-60 years) participating in organized (n=328) or high-risk (n=44) sports were recruited. Sports-related and clinical data were obtained by phone interview and medical records.