Publications by authors named "Cherry P Fernandez-Colorado"

Importance: African swine fever (ASF) is a contagious transboundary swine disease that poses a significant threat to the swine industry. As an archipelago, the Philippines has a geographic advantage in reducing ASF transmission risk. However, control efforts remain challenging due to the disease's complex epidemiology, lack of effective treatment, and vaccine availability.

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African swine fever (ASF) is a contagious hemorrhagic disease affecting both domestic and wild pigs with high mortality rate and severe socio-economic losses. Due to the virus' potential ability to remain infectious in suitable conditions and environments, it is imperative to identify risk factors that may contribute to its transmission. The Philippines' current ASF surveillance relies on pig blood samples.

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African swine fever (ASF), a highly contagious disease of swine, has posed a significant global threat to the swine industry. As an archipelago, the Philippines has a geographic advantage when it comes to the risk of ASF transmission. However, since its introduction to the Philippines in 2019, it has proliferated not only in backyard and commercial farms but also in wild pig populations.

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(RA) is an economically important pathogen in the duck industry worldwide that causes high mortality and morbidity in infected birds. We previously found that upregulated IL-17A expression in ducks infected with RA participates in the pathogenesis of the disease, but this mechanism is not linked to IL-23, which primarily promotes Th17 cell differentiation and proliferation. RNA sequencing analysis was used in this study to investigate other mechanisms of IL-17A upregulation in RA infection.

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Article Synopsis
  • - Three key factors (body weight gain, intestinal lesion score, and fecal oocyst shedding) were analyzed in broilers infected with major parasites, revealing differences in their impact based on age and gender of the birds.
  • - Two-week-old chickens exhibited a stronger correlation between intestinal lesion score and body weight gain when infected with Eimeria, as opposed to older chickens.
  • - Broilers infected with a specific parasite showed a more significant connection between body weight gain and intestinal lesion score, highlighting the importance of considering gender, age, and species in related experiments.
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is one of the most devastating pathogens affecting the global duck farms. Infection is involved in secretion of proinflammatory cytokines, including interleukin- (IL-) 17A. During the immune response to infection, IL-22 and IL-17A are often produced concurrently and at high levels in inflamed tissues.

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Coccidiosis in chickens is an intestinal parasitic disease caused by protozoan parasites named Eimeria spp. In some Eimeria infections, intestinal lymphocytes are known to highly express chicken NK-lysin (cNK-lysin), an antimicrobial peptide with anticoccidial activity. Therefore, this study aims to investigate the expression of cNK-lysin in E.

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3,3'-Diindolylmethane (DIM) is found in cruciferous vegetables and is used to treat various inflammatory diseases because of its potential anti-inflammatory effects. To investigate effects of DIM in Riemerella anatipestifer-infected ducks which induce upregulation of inflammatory cytokines, ducks were treated orally with DIM at dose of 200 mg/kg/day and infected the following day with R. anatipestifer.

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Riemerella anatipestifer causes infectious disease and considerable economic loss in the duck industry worldwide. Our previous studies demonstrated an association between proinflammatory cytokine interleukin (IL)-17A and R. anatipestifer infection.

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R. anatipestifer (RA) is one of the most harmful bacterial pathogens affecting the duck industry, and infection is associated with the production of proinflammatory cytokines, including IL-17A. Another proinflammatory cytokine, IL-23, is critical for the development of Th17 cells, which produce IL-17.

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