Effects of timolol on Ca handling and viability in human prostate cancer cells.

Timolol is a medication used widely to treat glaucoma. Regarding Ca signaling, timolol was shown to modulate Ca-related physiology in various cell types, however, the effect of timolol on Ca homeostasis and cell viability has not been explored in human prostate cancer cells. The aim of this study was to explore the effect of timolol on intracellular Ca concentrations ([Ca]) and viability in PC3 human prostate cancer cells.