[Treatment of septic complications of thoracic injuries].

Treatment results of 77 patients with suppurative lung complications after injuries (n=22) and closed thoracic trauma (n=55) were analyzed. It was registered, that purulent process in lung was typical for the cases with direct primary lung tissue injury: 72.7% of patients with penetrating thoracic injuries and 83.

[Pattern dynamics of bacteriemia and sepsis pathogens in ICU patients of emergency service].

The results of microbiological tests of 2382 blood specimens from 698 patients of three ICUs of the N. V. Sklifosovsky Research Institute of Emergency Service were analysed for a period of 2009 to 2012.

[Estimation of MRSA susceptibility to oxacillin, cefoxitine, vancomycin and daptomycin].

Prevalence and therapy of infections due to MRSA remain one of the most serious problems in the world. Therefore, correct laboratory identification of the MRSA phenotype based on the use of the marker antibiotic cefoxitine, as a more susceptibile one vs. oxacillin, is of great importance.

[The treatment of pulmonary bleedings and its' complicsations by the blunt thoracic trauma].

The experience of treatment of 224 patients with pulmonary bleeding after the blunt thoracic trauma were analyzed. All patients were diagnosed with lung contusion, of them 134 had traumatic cavities (hematomas) in the lung. The complete regression of contusion foci was observed within 13.

[The surgical treatment of the pleural empyem].

The treatment results of the 286 patients with pleural empyem after thoracic injuries (n=107) and closed trauma of the pleural cavity (n=179) were retrospectively analyzed. The frequency of pleural empyem was 1.39% by injuries and 1.

[Antibiotic susceptibility of isolates from blood of patients in intensive care units of emergency medical service].

The microbiological tests of 769 blood samples from 220 patients, treated in 4 intensive care units of the N.V. Sklifosovsky Research Institute for Emergency Medical Service within a period from January 2009 to June 2010, were analysed.

[Septic complications of the closed thoracic trauma].

210 cases of septic complications after blunt thoracic injuries were analyzed. Pleura empyem was observed in 172 (1,34%) of 12874 patients (overall number of the injuried), lung abscess - in 48 (0,37%) cases, pericarditis was diagnosed in 33 (0,23%) patients, costal and sternal osteomyelitis - in 21 (0,16%) and mediastinitis - in 14 (0,1%), thoracic wall phlegmona in 50 (0,39%) patients. Overall frequency of septic complication was 2,96%.

[Diagnostics and treatment of posttraumatic septic costal osteomyelitis].

Results of treatment and diagnostics of 47 patients with posttraumatic septic costal osteomyelitis were analyzed. 26 patients had open and 21 - closed thoracic injuries. Major reasons of osteomyelitis tended to be the initial infection of the bony injury, pleural surgical revision through the initial wound and late medical help by the closed thoracic injuries.

[Diagnostics and surgical treatment of the posttraumatic septic mediastinitis].

Treatment results of 38 cases of septic mediastinitis for the last 17 years were analyzed. The frequency of mediastinitis as a complication of the penetrating wound was 0.28%, and of the closed thoracic trauma - 0.

[Septic complications of penetrating thoracic injuries].

224 cases of septic complications after penetrating thoracic injuries were analyzed. Pleura empyem was observed in 105 of 7572 patients (overall number of the injured), lung abscess - in 22 cases, pericarditis was diagnosed in 108 patients, costal and sternal osteomyelitis - in 26 and mediastinitis - in 21 patients. Overall frequency of septic complication was 2,96%.

[Mono- and associated microflora during wound infection in patients with burns].

Aim: To study etiologic role of microorganisms during wound infection and elucidation of their populations interaction in patientswith burns.

Materials And Methods: 2137 patients with wound infection treated in burn center were studied. 3179 samples of wound exudates and 6501 strains of microorganisms were studied.

[Microbiological evaluation of differences between cephalosporins of second and third generations in general hospital].

The aim of the current investigation was to evaluate practical impact of modern NCCLS recommendations for the selection of 2nd and 3rd generation cephalosporins in Moscow teaching multi profile hospital. The sensitivity of clinically significant 96 strains from patients with pyelonephritis and 180 strains from patients with lower respiratory tract infections (pneumonia, COPD) was compared for cefuroxime and cefotaxime or ceftriaxone according NCCLS recommendations during 2000-2001 years. At the lower respiratory tract infection total sensitivity of all pathogens was 70.

[Microbiological evaluation of antibiotics for empirical therapy of community-acquired infections of the lower respiratory tract].

During first 3 days after patient hospitalization with pneumonia or chronic obstruction pulmonary disease (COPD) pathogens in sputum were studied according NCCLS standards (for 1999 year). Among 93 pathogens isolated in pneumonia the most frequent were S. pneumoniae (41.

[Enterobacterial sensitivity to beta-lactam antibiotics].

The susceptibility to betalactams of 868 enteric bacteria isolated from the patients at the hospital was studied. The isolated pathogens included: E. coli (549), Klebsiella sp.

[Effect of piperacillin/tazobactam on the anti-infection resistance in patients with infections in the peritoneal cavity].

The effect of the monotherapy with piperacillin/tazobactam (P/T) or tazocin on microflora of the mucous membranes of the nose and pharynx of 33 patients and the contents of the large intestine of 21 patients as well as on the immunological aspects (cellular and humoral factors) of the antiinfectious resistance systems (AIRS) in patients with abdominal cavity infection (ACI) was studied. Before the treatment serious impairment of the AIRS in all the patients was observed. The P/T monotherapy in a daily dose of 12/1.

[Use of microtest systems for identification of newly isolated clinical strains].

Species appurtenance of 425 clinical strains isolated from various types of material from December 1993 to November 1994 was identified using Lachema (Czechia) Micro-la-test. There were 99 staphylococcal, 139 streptococcal, 119 enterobacterial cultures, and 68 nonfermenting gram-negative bacteria. The microorganisms were characterized completely according to their code in 67.

[A method of sequential (intravenous and oral) use of ofloxacin in the treatment of patients with infections of organs of the peritoneal cavity].

Clinico-laboratory estimation of the efficacy and tolerance of ofloxacin used in succession, at first intravenously and then orally, in the treatment of 15 patients with infection of the abdominal cavity was performed. It was shown that after the use for a period of 10 years ofloxacin preserved its high antimicrobial activity against gram-positive and gram-negative organisms with multiple drug resistance and remained superior to the majority of broad spectrum antimicrobial agents by the number of susceptible isolates. The successive use of ofloxacin proved to be highly efficient.