[Toxic-allergic and viral hepatitis in patients with pulmonary tuberculosis].

Forty four patients with various forms of pulmonary tuberculosis in association with virus hepatitis B (21) and toxic-allergic hepatitis (23) were followed up in the time course of the diseases. There was a marked clinical similarity between toxic-allergic hepatitis and virus hepatitis B which differed in their qualitative indices and duration. Differential diagnosis of virus hepatitis B and toxic-allergic hepatitis was possible on the basis of the clinical signs and routine tests: determination of bilirubin and its fractions in blood, estimation of activity of alanine and aspartate aminotransferases and case follow-up with an account of the epidemiological situation.

[Effect of chronic nonspecific lung diseases on the detectability and course of tuberculosis].

Chronic nonspecific diseases of the respiratory organs frequently develop after clinical cure of tuberculosis, particularly in persons with ample residual changes which, in their turn, contribute to the development of a recurrence of tuberculosis. Recurrences were mainly detected during consultations in medical institutions. Therefore improved work with patients of the 7th registration group in antituberculous centers as well as with patients with chronic nonspecific diseases of the respiratory organs in the general medical network will contribute to a decrease in the number of tuberculosis recurrences or their earlier detection.

[Role of the teaching of phthisiology in raising the quality of the training of the general practitioner].

The teaching of a cycle of phthisiological pulmonology to undergraduates should be based on the principle of the retention of knowledge of phthisiology. In the 4th and 6th year great emphasis should be placed on the clinical signs of tuberculosis and the physician's role in the detection of tuberculosis.

[Correlation of the changes in the calorimetric indices of energy metabolism and of the morphofunctional changes in the thyroid gland of rats with various forms of experimental obesity].

Changes in heat exchange were compared with the morphofunctional changes of the thyroid gland in rats with various forms of experimental adiposity. Reduction of the hormone-forming function of the thyroid gland proved to correlate with the changes in heat formation and thermoregulation, and corresponded to the degree of adiposity observed.

[Change in calorimetric indicators of energy metabolism and thermoregulation reaction in obese albino rats].

A study was made of the changes in the calorimetric indices of the energy metabolism (heat emission, "direct" thermoproduction and body temperature) in albino rats with adiposity due to overfeeding and ovariectomy. From the age of 4 months an additional feeding of highly caloric food to normal and ovariectomized animals led to a marked and significant gain in weight. There were marked quantitative changes in the calorimetric indices and the reaction of thermoregulation expressed both in a significant reduction of the initial values of thermal emission, heat production and body temperature, and in the chnages of the reactive peculiarities of heat exchange: reduction of heat emission, diminished accretion of heat production and of the rate of restoration of body temperature after functional "cold" test--in comparison with such in normal animals.

[Adipose tissue sensitivity to insulin in obese ovariectomized rats].

A study was made of sensitivity of the isolated adipose tissue in rats with ovariectomy and overfeeding. Insulin sensitivity was assessed by the intensity of glucose-C14 incorporation into total lipids of adipose tissue in its incubation with insulin in a concentration of 100 minutes/ml. It was demonstrated that 3 1/2 months after the operation no adiposity developed in ovariectomized rats and insulin sensitivity of the adipose tissue persisted at the normal level.

[The state of heat exchange and thermoregulation in animals castrated at different ages].

A change of the indices of thermal metabolism and of thermoregulation in male rats with reduction of the gonad function in the aging animals and following castration at different age was studied by means of calorimetric unit permitting to record total heat emission, "direct" heat production, and also the body temperature of the animals in experiments of any duration. Functional "cold" test was used to assess the adaptive possibilities of thermoregulation. Old unoperated males showed a reduction of background values of heat exchange, diminished increase of the indices of heat production and lesser rate of body temperature restoration following the "cold" test.