Synopsis of recent research by authors named "Cheon Ik Park"
- Cheon Ik Park's research primarily focuses on the expression and characterization of human cytotoxic T-lymphocyte antigen 4-immunoglobulin (hCTLA4Ig) in transgenic rice cell suspension cultures as a potential immunosuppressive therapeutic agent.
- His findings highlight the successful expression of hCTLA4Ig with improved glycan structures that enhance serum half-life and reduce immunogenic responses when compared to traditional Chinese hamster ovary cell-derived hCTLA4Ig.
- The studies also demonstrate comparable in vitro immunosuppressive activities of rice cell-derived hCTLA4Ig and CHO-derived counterparts, marking a significant advancement in the field of plant-based biopharmaceuticals.