Oscillating Fluid Flow Activated Osteocyte Lysate-Based Hydrogel for Regulating Osteoblast/Osteoclast Homeostasis to Enhance Bone Repair.

As major regulators on bone formation/resorption in response to mechanical stimuli, osteocytes have shown great promise for restoring bone injury. However, due to the unmanageable and unabiding cell functions in unloading or diseased environments, the efficacy of osteogenic induction by osteocytes has been enormously limited. Herein, a facile method of oscillating fluid flow (OFF) loading for cell culture is reported, which enables osteocytes to initiate only osteogenesis and not the osteolysis process.

In vitro and in vitro toxicity study of diesel exhaust particles using BEAS-2B cell line and the nematode Caenorhabditis elegans as biological models.

It is well accepted that diesel exhaust particles (DEPs) are highly associated with improper function of organ systems. In this study, DEP toxicity was performed by using in vitro human BEAS-2B cell line and in vivo animal model, namely, Caenorhabditis elegans (C. elegans).

Nonylphenol induced individual and population fluctuation of Caenorhabditis elegans: Disturbances on developmental and reproductive system.

The environmental risks that have arisen from endocrine disruption compounds (EDCs) have become global challenges, especially for persistent bio-accumulated xenobiotic chemicals, such as nonylphenol (NP). In the present study, the population dynamics of Caenorhabditis elegans (C. elegans) were systemically investigated by conducting developmental and reproductive bioassays under the exposure of NP, which has been widely detected in actual aquatic environments.

Photolysis-Induced Neurotoxicity Enhancement of Chlorpyrifos in Aquatic System: A Case Investigation on .

Contamination of the environment by toxic pesticides has become of great concern in agricultural countries. Chlorpyrifos (CP) is among the pesticides most commonly detected in the environment owing to its wide agricultural applications. The aim of this study was to compare potential changes in the toxicity of CP after irradiation.