Comparative study of synergistic antibacterial activity of ciprofloxacin-capped gold nanoparticles under different ultrasound frequency.

Sonodynamic antimicrobial chemotherapy (SACT), as a novel anti-infective program, has received tremendous attention due to its good tissue penetration depth and low invasion. Ultrasound (US) frequency was one of the important parameters for SACT. To investigate the influence of different US frequencies on sonodynamic antimicrobial activity of ciprofloxacin-capped gold nanoparticles (CIP:GNPs).

Synthesis of Ciprofloxacin-capped Gold Nanoparticles Conjugates with Enhanced Sonodynamic Antimicrobial Activity in vitro.

The purpose of this article is to discuss whether gold nanoparticles (GNPs) play an auxo-action on ciprofloxacin (CIP)-mediated sonodynamic antimicrobial chemotherapy (SACT) in vitro. The measuring criterion of SACT, bactericidal efficiency, was measured by plate colony-counting methods. According to research findings, the duration of ultrasound (US) exposure, solution temperature and CIP:GNPs concentration were all critical influencing factors of SACT.