Publications by authors named "Chenyi Zeng"

Semiconductor-based photoelectrochemical (PEC) test protocols offer a viable solution for developing efficient individual health monitoring by converting light and chemical energy into electrical signals. However, slow reaction kinetics and electron-hole complexation at the interface limit their practical application. Here, we reported a triple-engineered CdS nanohierarchical structures (CdS NHs) modification scheme including morphology, defective states, and heterogeneous structure to achieve precise monitoring of the neurotransmitter dopamine (DA) in plasma and noninvasive body fluids.

View Article and Find Full Text PDF

The characteristics of DNA hybridization enable molecular computing through strand displacement reactions, facilitating the construction of complex DNA circuits, which is an important way to realize information interaction and processing at a molecular level. However, signal attenuation in the cascade and shunt process hinders the reliability of the calculation results and further expansion of the DNA circuit scale. Here, we demonstrate a novel programmable exonuclease-assisted signal transmission architecture, where DNA strand with toehold employed to inhibit the hydrolysis process of EXO λ is applied in DNA circuits.

View Article and Find Full Text PDF
Article Synopsis
  • Uric acid (UA) is crucial for disease prevention, and there's a need for quick and accurate detection methods.
  • Researchers have created manganese dioxide nanosheets (MnONSs) that change color in response to UA, allowing for an enzyme-free colorimetric sensing system.
  • The detection system is highly sensitive (with limits down to 0.047 μmol/L), has a wide range (0.10-50.0 μmol/L), and has been successfully tested on human serum and urine samples.
View Article and Find Full Text PDF

Automatic vertebra recognition from magnetic resonance imaging (MRI) is of significance in disease diagnosis and surgical treatment of spinal patients. Although modern methods have achieved remarkable progress, vertebra recognition still faces two challenges in practice: (1) Vertebral appearance challenge: The vertebral repetitive nature causes similar appearance among different vertebrae, while pathological variation causes different appearance among the same vertebrae; (2) Field of view (FOV) challenge: The FOVs of the input MRI images are unpredictable, which exacerbates the appearance challenge because there may be no specific-appearing vertebrae to assist recognition. In this paper, we propose a Feature-cOrrelation-aware history-pReserving-sparse-Coding framEwork (FORCE) to extract highly discriminative features and alleviate these challenges.

View Article and Find Full Text PDF
Article Synopsis
  • Building synthetic molecular circuits can lead to advancements in ion detection, information processing, and molecular computing, but implementing NOT logic with a single molecule input is challenging.
  • For the first time, a new approach using lambda exonuclease proposes a switching strategy that allows circuits to output opposite logic based on the presence or absence of a signal, with time-responsive features based on the order and timing of signals.
  • The design also includes a time-delay relay for delayed disconnection and output control, showcasing versatility by enabling the construction of more complex digital circuits, promising applications in information processing and nanomachines.
View Article and Find Full Text PDF

The construction of logic circuits is critical to DNA computing. Simple and effective scalability methods have been the focus of attention in various fields related to constructing logic circuits. We propose a double-stranded separation (DSS) strategy to facilitate the construction of complex circuits.

View Article and Find Full Text PDF

In recent years, there have been multiple works of literature reviewing methods for automatically segmenting multiple sclerosis (MS) lesions. However, there is no literature systematically and individually review deep learning-based MS lesion segmentation methods. Although the previous review also included methods based on deep learning, there are some methods based on deep learning that they did not review.

View Article and Find Full Text PDF

Background: Sudden hearing loss is an emergency health problem in the Department of Otolaryngology that must be treated in a timely manner, or may cause lifelong regrets. The application of postauricular injection of glucocorticoid is a popular treatment to recover patients hearing level in recent years. However, the effectiveness and safety of postauricular injection of glucocorticoid needs to be assessed systematically.

View Article and Find Full Text PDF