Publications by authors named "Chenxin Zeng"

Adult animals are unable to regenerate heart cells due to postnatal cardiomyocyte cycle arrest, leading to higher mortality rates in cardiomyopathy. However, reprogramming of energy metabolism in cardiomyocytes provides a new perspective on the contribution of glycolysis to repair, regeneration, and fibrosis after cardiac injury. Pyruvate kinase (PK) is a key enzyme in the glycolysis process.

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Article Synopsis
  • The analysis of dynamic targets requires quick capture of both spatial and spectral visual information, leading to the development of snapshot spectral imaging technologies.
  • Our new dual-channel snapshot imaging spectrometer (DSIS) effectively combines a wide spectral range with high resolution in a compact design.
  • By using a dual-channel method to separate the spectral range and optimizing the field of view, DSIS improves image quality while accommodating up to 250 spectral channels across a 400 to 795 nm range.
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  • A new type of imaging tool called the TIF-SIS is introduced, which significantly improves dynamic tracking and real-time recognition compared to traditional methods.
  • This tool allows for adjustable spatial and spectral resolutions, addressing a common limitation in existing imaging techniques.
  • Experimental results validate its capabilities, showing enhanced spectral resolution and light throughput, making it ideal for applications like biomedical research and detecting subtle spectral signatures.
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  • Recent trends in push-broom imaging spectrometers focus on high spectral resolution and compact designs, with the concentric Offner imaging spectrometer gaining popularity for its optical performance.
  • Astigmatism remains a major issue for Offner spectrometers, leading to poor image quality and compromised spectral resolution.
  • This paper presents a compact Offner imaging spectrometer using an aberration-reduced convex holographic grating (ACHG), which enhances image quality and spectral resolution by balancing holographic and geometric aberrations.
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Requirements for wide field of view (FOV) imaging system reflect the need for both uniform illumination as well as excellent image quality across the entire FOV. As the monocentric lens combined with a parallel array of relay imagers achieves a wide-FOV while maintaining a high resolution, we studied the monocentric cascade imaging system (MCIS). However, the imaging experiment of the prototype shows two issues, including vignetting and non-uniform image quality over the full FOV.

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Aim: To evaluate the cost-utility of gefitinib and afatinib as first-line EGFR-mutated non-small-cell lung cancer treatments from the Chinese healthcare system perspective.

Materials & Methods: A Markov model was established, state transition probabilities were extracted from the LUX-Lung7 trial and utility values were from previous studies. The cost was extracted from local charge or relevant literature.

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