Publications by authors named "Chenxiang Luo"
Article Synopsis
- NUT carcinoma (NC) is a severe cancer without effective treatments, often linked to specific chromosome translocations that create a fusion gene.
- Researchers have developed a genetically engineered mouse model that mimics the human t(15;19) translocation, showing it can trigger aggressive carcinomas in mice.
- The tumors in these mice share key characteristics with human NC, indicating that the model can help in understanding the disease and developing potential therapies.
In order to find out to what extent ovarian aging could be compensated by the fertilization/intracytoplasmic sperm injection (IVF/ICSI) treatments, a total of 4102 women above the age of 35 undergoing 6489 complete cycles from 2009 to 2015 with follow-up visits until 2017 were retrospectively analyzed. Cumulative live birth rates (CLBRs) across multiple IVF/ICSI cycles were compared in the study population stratified by age and ovarian reserve (classified by the POSEIDON criteria). Younger patients (aged between 35 and 40) could well benefit from repeat IVF treatments, with the optimal CLBRs ranging from 62%-72% for up to four complete cycles.
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