Parental emotional neglect and academic procrastination: the mediating role of future self-continuity and ego depletion.

The purpose of this study was to explore the effect of parental emotional neglect on the academic procrastination of late adolescents and further analyze the mediating role of future self-continuity and ego depletion. This study included 609 college students, 344 males and 265 females, ranging in age from 17 to 21 years ( = 18.39,  = 0.

Negative association between harsh parenting and life satisfaction: negative coping style as mediator and peer support as moderator.

Background: Previous research has demonstrated that harsh parenting negatively affects children's psychological development. This study examined the association between harsh parenting during childhood and life satisfaction of Chinese college students. We further looked at whether this association is explained in part by negative coping styles, and whether peer support lessens the potential effect of harsh parenting on negative coping styles and life satisfaction.

Hypoxic colorectal cancer cells promote metastasis of normoxic cancer cells depending on IL-8/p65 signaling pathway.

Tumor heterogeneity is an important feature of malignant tumors, and cell subpopulations may positively interact to facilitate tumor progression. Studies have shown that hypoxic cancer cells possess enhanced metastatic capacity. However, it is still unclear whether hypoxic cancer cells may promote the metastasis of normoxic cells, which have greater access to the blood circulation.

Distribution of Metastatic Cancer Cells in Colorectal Mesentery.

Background: To investigate the distribution of metastatic cancer cells in the mesentery (referred to as metastasis V) and enrich the understanding of the metastasis of colorectal cancer.

Methods: A total of two hundred ninety-nine patients who received colorectal operations at the Department of Gastrointestinal Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology between April 2018 and December 2018 were included. Samples were acquired from the dissected mesentery after the operation, and hematoxylin-eosin staining or immunohistochemistry was used to detect metastatic cancer cells.

The CEA-/lo colorectal cancer cell population harbors cancer stem cells and metastatic cells.

Serum carcinoembryonic antigen (CEA) is the most commonly used tumor marker in a variety of cancers including colorectal cancer (CRC) for tumor diagnosis and monitoring. Recent studies have shown that colonic crypt cells expressing little or no CEA may enrich for stem cells. Numerous studies have clearly shown that there exist CRC patients with normal serum CEA levels during tumor progression or even tumor relapse, although CEA itself is considered to promote metastasis and block cell differentiation.